Omalizumab and adalimumab: a winning couple

L Diluvio, L Vollono, A Zangrilli, V Manfreda… - …, 2020 - Taylor & Francis
Introduction: We report a case of a young female patient, previously affected by psoriatic
arthritis, and treated with adalimumab, who developed a chronic spontaneous urticaria and …

[HTML][HTML] Quantitative in vitro and in vivo models to assess human IgE B cell receptor crosslinking by IgE and EMPD IgE targeting antibodies

B Vigl, N Salhat, M Parth, H Pankevych… - Journal of …, 2017 - Elsevier
Targeting plasma IgE by therapeutic mABs like Omalizumab (Xolair®) is current clinical
practice for severe allergic conditions or other IgE related diseases like chronic urticaria. As …

The Fab fragment of anti-IgE Cε2 domain prevents allergic reactions through interacting with IgE-FcεRIα complex on rat mast cells

T Hirano, A Koyanagi, K Kotoshiba, Y Shinkai… - Scientific reports, 2018 - nature.com
Immunoglobulin E (IgE) plays a central role in the pathogenesis of Type I hypersensitivity
through interaction with a high-affinity receptor (FcεRIα). For therapeutic applications …

[HTML][HTML] Recent insights into the management of treatment-resistant pediatric atopic dermatitis

PP Naik - International Journal of Women's Dermatology, 2022 - journals.lww.com
Atopic dermatitis (AD) is a prevalent protracted inflammatory skin condition that affects
approximately 12% of children globally. Topical remedies, such as pharmacologic and …

[HTML][HTML] The ratio of total IgE level at week 16 to baseline significantly correlated with the clinical response to omalizumab in moderate to severe allergic rhinitis …

Z Zhao, Y Deng, L Xiang, J Chen, J Wan, J Sun… - International …, 2023 - Elsevier
Objective To analyze whether the ratio of total IgE level at week 16 to baseline could be
used as an indicator to evaluate clinical efficacy of patients treated with omalizumab …

Novosti u liječenju astme u djece

M Turkalj, Ž Vlašić Lončarić - Liječnički vjesnik, 2023 - hrcak.srce.hr
Sažetak Astma u dječjoj dobi jest heterogena kronična upalna bolest donjih dišnih puteva
koja se očituje od rane životne dobi različitim fenotipovima i endotipovima, koji se mogu …

Smart Peptide Defense Web In Situ Connects for Continuous Interception of IgE against Allergic Rhinitis

MR Ding, QL Liang, HG Xu, XD Li… - … Applied Materials & …, 2022 - ACS Publications
Allergic rhinitis (AR) is a chronic inflammatory reaction by immunoglobulin E (IgE) mediators
after individual contact with allergens. It affects 10–40% of the world's population and …

Biological therapy of autoimmune blistering diseases

M Alaibac - Expert Opinion on Biological Therapy, 2019 - Taylor & Francis
Introduction: Autoimmune blistering skin diseases are a group of disorders subdivided
according to the location of blister formation: intraepidermal blistering in the pemphigus …

Eliminating Drug Target Interference with Specific Antibody or its F(ab′)2 Fragment in the Bridging Immunogenicity Assay

X Deng, Y Hou, W Yuan, H Yang, R Guo, T Liu, Y Liu… - Bioanalysis, 2024 - Taylor & Francis
Background: DB-1003 is a humanized anti-IgE monoclonal antibody with higher affinity than
omalizumab. In the affinity capture elution (ACE)-based bridging electrochemiluminescent …

Место омализумаба в терапии аллергических заболеваний

ОМ Курбачёва, МА Галицкая - Медицинский совет, 2019 - cyberleninka.ru
В статье описан современный подход к применению антиIgE-терапии при
аллергической бронхиальной астме и сопутствующих этому заболеванию состояниях …