Anaphylaxis, a life-threatening allergic reaction, is dependent on high affinity allergen-
specific IgE. Gowthaman et al. now show that a new interleukin (IL)-13-expressing T helper …

Background Mast cells are the major effector cell type for IgE-mediated allergic reactions.
Recent studies revealed a role for mast cells in orchestrating the host response to viral …

Background Histamine-releasing factor (HRF) is implicated in allergic diseases. We
previously showed its pathogenic role in murine models of asthma. Objective We aim to …

To investigate the influence of omalizumab combined with enteral nutrition in treating severe
allergic asthma, 102 patients in our hospital from May 2020 to May 2023 were …

Allergic diseases have a substantial epidemiological impact on pediatric population. Small
molecule-based medicines have been traditionally used to manage the diseases …

IgE protects the host against parasites and venoms; however, IgE also plays a central role in
the pathogenesis of allergic diseases. The high-affinity receptor for IgE, FcεRI, expressed on …

Immunoglobulin E (IgE) plays pivotal roles in allergic diseases through interaction with a
high-affinity receptor (FcεRI). We established that Fab fragments of anti-IgE antibodies (HMK …

Ce document est une mise à jour d'un précédent publié sur le site Papyrus de l'Université de
Montréal en 2023. Il tient compte des cibles thérapeutiques nouvelles ainsi que des …

This document is an update of a previous one published on the Papyrus site of the
University of Montreal in 2023. It takes into account new therapeutic targets as well as …

Immunoglobin E (IgE)-related allergy constitutes a high proportion in allergic diseases. The
production of specific IgE is key to evoking serial cascades and pathological reactions. Thus …