Recent reports indicate that statins are associated with an increased risk for new-onset
diabetes mellitus (DM) compared with placebo and that this relation is dose dependent. The …

Lowering low-density lipoprotein–cholesterol (LDL–C) is the primary target in the
management of dyslipidemia in patients at high risk of cardiovascular disease. However …

Address for correspondence: Soo Lim, Internal Medicine, Seoul National University College
of Medicine and Seoul National University Bundang Hospital, 300 Gumi-dong, Bundang-gu …

Background Statin treatment increases the risk of new-onset diabetes mellitus (NODM);
however, data directly comparing the risk of NODM among individual statins is limited. We …

Background A recent meta-analysis has reported that intensive-dose statin drug increases
the risk of incident diabetes. However, doubling of the statin dose generates only a further …

BACKGROUND: Rosuvastatin and pravastatin have differential hydrophilicity and potency to
inhibit hydroxymethylglutaryl-CoA reductase that may be relevant to changes in adiponectin …

282 LEE HY et al. comes, 15 recently published hypertension guidelines state that diuretics,
β-blockers, calcium antagonists, angiotensin-converting enzyme inhibitors (ACEIs) and …

Abstract Statins, 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors, are important
for preventing adverse cardiovascular events not only in patients with a high risk of vascular …

Background Statins have been known to increase the risk of incident type 2 diabetes
mellitus (DM); however, other factors, especially hypertension, are also associated with DM …

Elevated plasma low density lipoprotein (LDL) is an established risk factor for cardiovascular
disease. In addition to being able to cross the endothelial barrier to become accumulated in …