[HTML][HTML] Vortioxetine for cognitive enhancement in major depression: from animal models to clinical research

D Bennabi, E Haffen, V Van Waes - Frontiers in psychiatry, 2019 - frontiersin.org
Objectives: Vortioxetine has already shown its efficacy in the acute and long-term treatment
of major depressive disorder (MDD) and its potential interest in the prevention of relapse …

Effect of vortioxetine on cognitive impairment in patients with major depressive disorder: a systematic review and meta-analysis of randomized controlled trials

IC Huang, TS Chang, C Chen… - International Journal of …, 2022 - academic.oup.com
Background Dementia and depression are increasingly common worldwide, and their
effective control could ease the burden on economies, public health systems, and support …

[HTML][HTML] Systematic review and meta-analysis of vortioxetine for the treatment of major depressive disorder in adults

X Zhang, Y Cai, X Hu, CY Lu, X Nie, L Shi - Frontiers in Psychiatry, 2022 - frontiersin.org
Objective We aimed to compare the efficacy, acceptability, and tolerability of vortioxetine in
the treatment of Major Depressive Disorder (MDD) in adults. Method We searched PubMed …

Processing speed and sustained attention in bipolar disorder and major depressive disorder: A systematic review and meta‐analysis

B Little, M Anwyll, L Norsworthy, L Corbett… - Bipolar …, 2024 - Wiley Online Library
Objectives Cognitive impairment is a core feature of bipolar disorder (BD) and major
depressive disorder (MDD). Deficits in processing speed (PS) and sustained attention (SA) …

[HTML][HTML] The diagnostic value of the combination of serum brain-derived neurotrophic factor and insulin-like growth factor-1 for major depressive disorder diagnosis …

AS Troyan, OA Levada - Frontiers in Psychiatry, 2020 - frontiersin.org
Background Last decades of psychiatric investigations have been marked by a search for
biological markers that can clarify etiology and pathogenesis, confirm the diagnosis, screen …

Comparison of vortioxetine and sertraline for treatment of major depressive disorder in elderly patients: A double‐blind randomized trial

F Borhannejad, B Shariati, S Naderi… - Journal of Clinical …, 2020 - Wiley Online Library
What is known and objective Major depressive disorder (MDD) is a complex disease and
one of the leading contributors to disease burden throughout the world. In the current study …

Depression and cognitive function in early multiple sclerosis: multitasking is more sensitive than traditional assessments

L Glukhovsky, D Kurz, R Brandstadter… - Multiple Sclerosis …, 2021 - journals.sagepub.com
Background: Persons with multiple sclerosis (MS) and depression symptoms report real-
world cognitive difficulties that may be missed by laboratory cognitive tests. Objective: To …

Distinct association of plasma BDNF concentration and cognitive function in depressed patients treated with vortioxetine or escitalopram

M Sagud, M Nikolac Perkovic, A Dvojkovic, N Jaksic… - …, 2021 - Springer
Rationale Cognitive dysfunction is frequent in major depressive disorder (MDD), and brain-
derived neurotrophic factor (BDNF) is involved both in regulation of cognition and in …

[HTML][HTML] Review of antidepressants in clinic and active ingredients of traditional Chinese medicine targeting 5-HT1A receptors

L Wang, Y Zhang, X Du, T Ding, W Gong… - Biomedicine & …, 2019 - Elsevier
Serotonin, which also named as 5-hydroxytryptamine (5-HT), is a neurotransmitter, which
plays significant roles in a wide range of physiological and pathological processes …

Contributors of functional impairment in major depressive disorder: a biopsychosocial approach

TK Chow, CR Bowie, M Morton, A Lalovic… - Current Behavioral …, 2022 - Springer
Abstract Purpose of Review This narrative review summarizes the current evidence
regarding functional impairment in MDD and the factors contributing to it. Recent Findings …