Cancer is the second leading cause of death worldwide. Differences in drug resistance and
treatment response caused by the heterogeneity of cancer cells are the primary reasons for …

Microfluidic systems have been widely used in various in vitro tissue engineering models. In
this paper, we present a new microfluidic system for manufacturing cell filaments laden with …

Vascularized organoid-on-a-chip (VOoC) models achieve substance exchange in deep
layers of organoids and provide a more physiologically relevant system in vitro. Common …

Construction of in vitro vascular models is of great significance to various biomedical
research, such as pharmacokinetics and hemodynamics, and thus is an important direction …

Cancer immunotherapy has emerged as a promising therapeutic strategy to combat cancer
effectively. However, it is hard to observe and quantify how this in vivo process happens …

3D cell culture can mimic tumor pathophysiology, which reflects cellular morphology and
heterogeneity, strongly influencing gene expression, cell behavior, and intracellular …

Currently, researchers have increasingly focused on 3D in vitro tumor models as they
possess the capacity to replicate tissue-like characteristics and cell-cell interactions within …

Label-free cell classification is advantageous for supplying pristine cells for further use or
examination, yet existing techniques frequently fall short in terms of specificity and speed. In …

Vascularized tumor on a chip (VToC) entails emulating intricate microvascular networks like
those observed in tumors through microfluidic devices, which are meticulously designed to …

Vascular system is involved in various essential life activities, including both normal
embryonic organ development and pathological processes, such as tumorigenesis. In …