Biomonitoring exposure and early diagnosis in silicosis: a comprehensive review of the current literature

IM Căluțu, RA Smărăndescu, A Rașcu - Biomedicines, 2022 - mdpi.com
Silicosis is a particular form of lung fibrosis attributable to occupational exposure to
crystalline silica. The occupational exposure to crystalline silica also increases the risk of …

Characterization and toxicity analysis of lab-created respirable coal mine dust from the appalachians and rocky mountains regions

V Salinas, M Das, Q Jacquez, A Camacho… - Minerals, 2022 - mdpi.com
Coal mine workers are continuously exposed to respirable coal mine dust (RCMD) in
workplaces, causing severe lung diseases. RCMD characteristics and their relations with …

Protective effects of oleanolic acid on oxidative stress and the expression of cytokines and collagen by the AKT/NF‑κB pathway in silicotic rats

HB Peng, RX Wang, HJ Deng… - Molecular …, 2017 - spandidos-publications.com
Oleanolic acid (OA), a natural pentacyclic triterpenoid, has been reported to have several
benefits and medicinal properties. However, its protective effects against silica‑induced lung …

Proinflammatory and anti-inflammatory cytokines in adolescents from Southeast Bulgarian cities with different levels of air pollution

ZG Dobreva, GS Kostadinova… - Toxicology and …, 2015 - journals.sagepub.com
Epidemiological studies demonstrated that the exposure of different air pollutants including
particulate matter (PM) has been related to adverse effect on immune system. Current study …

Inflammatory and oxidative stress biomarkers induced by silica exposure in crystal craftsmen

AP Scalia Carneiro, E Algranti… - American journal of …, 2020 - Wiley Online Library
Background Identification of biomarkers associated with the diagnosis and prognosis of
silicosis would be highly advantageous in the clinical setting. The aim of this study is to …

Capsaicin reduces PLGA‐induced fibrosis by promoting M2 macrophages and suppressing overall inflammatory Response

T Truong, KS Jones - … of Biomedical Materials Research Part A, 2018 - Wiley Online Library
Capsaicin reduced poly (lactic‐co‐glycolic) acid (PLGA)‐induced fibrosis by promoting IL‐
10 secretion and suppressing alpha‐smooth muscle actin (α‐SMA) expression. The lifetime …

Evaluation of oxidative stress parameters and genotoxic effects in patients with work-related asthma and silicosis

OK Kurt, D Ergun, HG Anlar, M Hazar… - … of Occupational and …, 2023 - journals.lww.com
Objective To determine the mechanistic roles of oxidative stress, inflammation, and
genotoxicity parameters in patients with work-related asthma (WRA) and silicosis. Methods …

Highly sensitive lab on a chip (LOC) immunoassay for early diagnosis of respiratory disease caused by respirable crystalline silica (RCS)

VT Upaassana, S Ghosh, A Chakraborty… - Analytical …, 2019 - ACS Publications
Respirable crystalline silica (RCS) produced in mining and construction industries can
cause life-threatening diseases such as silicosis, lung cancer, and chronic obstructive …

[HTML][HTML] Impaired interferon-γ signaling promotes the development of silicosis

Z Peng, M Duan, Y Tang, J Wu, K Zhao, Y Zhong, Z He… - Iscience, 2022 - cell.com
Silicosis is caused by inhalation of crystalline silica dust particles and known as one of the
most serious occupational diseases worldwide. However, little is known about intrinsic …

A toxicological study of the respirable coal mine dust: assessment of different dust sources within the same mine

M Das, V Salinas, J LeBoeuf, R Khan, Q Jacquez… - Minerals, 2023 - mdpi.com
Respirable coal mine dust (RCMD) exposure is one of the utmost health hazards to the
mining community causing various health issues, including coal worker pneumoconiosis …