A review on comparative study of PPI and PAMAM dendrimers

D Kaur, K Jain, NK Mehra, P Kesharwani… - Journal of Nanoparticle …, 2016 - Springer
Dendrimers are hyperbranched, monodispersed macromolecules with multivalent functional
end groups. Dendrimers have been explored as carrier for many drugs like anticancer …

The therapeutic efficacy of dendrimer and micelle formulations for breast cancer treatment

S Alven, BA Aderibigbe - Pharmaceutics, 2020 - mdpi.com
Breast cancer is among the most common types of cancer in women and it is the cause of a
high rate of mortality globally. The use of anticancer drugs is the standard treatment …

Inhibition of hIAPP amyloid aggregation and pancreatic β‐cell toxicity by OH‐terminated PAMAM dendrimer

EN Gurzov, B Wang, EH Pilkington, P Chen, A Kakinen… - Small, 2016 - Wiley Online Library
Human islet amyloid polypeptide (hIAPP, or amylin) forms amyloid deposits in the islets of
Langerhans, a phenomenon that is associated with type‐2 diabetes impacting millions of …

PAMAM and polyester dendrimers as favipiravir nanocarriers: a comparative study using DFT method

S Bazyari-Delavar, F Badalkhani-Khamseh… - Journal of Nanoparticle …, 2021 - Springer
The electronic sensitivity and reactivity of polyamidoamine (PAMAM) and polyester
dendrimers toward favipiravir (T705) were inspected using density functional theory method …

The effect of PAMAM dendrimers on the antibacterial activity of antibiotics with different water solubility

K Winnicka, M Wroblewska, P Wieczorek, PT Sacha… - Molecules, 2013 - mdpi.com
Erythromycin (EM) and tobramycin (TOB) are well-known and widely used antibiotics,
belonging to different therapeutic groups: macrolide and aminoglycoside, respectively …

Acetyl-terminated PAMAM dendrimers for pH-sensitive delivery of irinotecan and fluorouracil: A molecular dynamics simulation study

CY Hsu, AA Rajhi, E Ali, S Chandra, HH Ahmed… - Chemical Physics …, 2023 - Elsevier
Acetyl-terminated poly (amidoamine) dendrimer (G4ACE) was investigated as a pH-
responsive nanocarrier for co-delivery of irinotecan (IRI) and fluorouracil (FU) using …

PEGylated dendrimer mediated delivery of bortezomib: drug conjugation versus encapsulation

RK Sahoo, A Gothwal, S Rani, KT Nakhate… - International Journal of …, 2020 - Elsevier
Poor aqueous solubility of anticancer drug bortezomib (BTZ) still remains a major challenge
in the development of a successful formulation. The dendrimeric platform can provide a …

Dendritic nanoparticles: the next generation of nanocarriers?

RM Pearson, S Sunoqrot, H Hsu, JW Bae… - Therapeutic …, 2012 - Future Science
Dendritic polymers have attracted a great deal of scientific interest due to their well-defined
unique structure and capability to be multifunctionalized. Here we present a comprehensive …

Recent advances in targeted drug delivery approaches using dendritic polymers

J Bugno, H Hsu, S Hong - Biomaterials science, 2015 - pubs.rsc.org
Since they were first synthesized over 30 years ago, dendrimers have seen rapid translation
into various biomedical applications. A number of reports have not only demonstrated their …

Theoretical evaluation of poly (amidoamine) dendrimers with different peripheral groups as a purinethol drug delivery system in aqueous medium

R Al-Shdefat, MM Kadhim, AB Mahdi, HA Lafta… - Colloids and Surfaces B …, 2022 - Elsevier
In this work, density functional theory calculations were used to study the association of PUR
with amine-and acetyl-terminated PAMAM dendrimers considering implicit solvent effect at …