Background: Cancer accounts for several deaths each year. There are multiple FDA
approved drugs for cancer treatments. Due to the severe side effects and multiple drug …

Triple-negative breast cancer (TNBC) is the most aggressive type of cancer, with a high risk
of death on recurrence. To date, there is a lack of approved targeted agents for the treatment …

Here, we report the structural optimization of a hit natural compound, 2-ME 2 (2-
methoxyestradiol), which exhibited inhibitory activity but low potency on tubulin …

1, 8-naphthyridine-3-carboxamide structures were previously identified as a promising
scaffold from which to obtain CB2R agonists with anticancer and anti-inflammatory activity …

In this work, we synthesized a series of indole derivatives to cope with the current increasing
fungal infections caused by drug-resistant Candida albicans. All compounds were evaluated …

Low-density lipoprotein receptor class A domain containing 2 (LDLRAD2) acts as a protein-
coding gene in a large number of human diseases. However, the potential roles and …

Objectives The most effective method currently used in breast cancer diagnosis is fine-
needle aspiration biopsy. However, if the superiority of serum molecular markers to invasive …

Indole, a versatile outstanding heterocyclic compound, engaged in numerous
pharmacological properties due to their multiple biochemical processes. The remarkable …

Targeting foremost molecular signaling pathways regulating tumor development with
phytochemicals - Book chapter - IOPscience This site uses cookies. By continuing to use this site …

Next to cardiovascular disease, cancer remains the second leading cause of mortality and
morbidity in the world. Breast cancer is the leading cancer type in women. The high rates of …