Anti-cytokine autoantibodies (ACAAs) are increasingly recognized as modulating disease
severity in infection, inflammation and autoimmunity. By reducing or augmenting cytokine …

Abstract The type I IFN (IFN‐I) system is essential to limit severe viral disease in humans.
Thus, IFN‐I deficiencies are associated with serious life‐threatening infections. Remarkably …

Some individuals do not return to baseline health following SARS-CoV-2 infection, leading
to a condition known as long COVID. The underlying pathophysiology of long COVID …

Summary Background Children with SARS-CoV-2 related Multisystem Inflammatory
Syndrome in Children (MIS-C) often present with clinical features that resemble Kawasaki …

The role of the autoimmune regulator (Aire) in central immune tolerance and thymic self-
representation was first described more than 20 years ago, but fascinating new insights into …

The host immune response against severe acute respiratory syndrome coronavirus 2
includes the induction of a group of natural antiviral cytokines called interferons (IFNs) …

Introduction Impairment of the type I interferon (IFN–I) signaling pathway is associated with
increased severity of COVID-19 disease. Here we have undertaken a systematic review and …

Background: The SARS-CoV-2 infection is now a part of the everyday lives of
immunocompromised patients, but the choice of treatment and the time of viral clearance …

Circulating follicular helper T cells (cTfh) can show phenotypic alterations in disease
settings, including in the context of tissue-damaging autoimmune or anti-viral responses …

Anticytokine autoantibodies (ACAAs) are a fascinating group of antibodies that have gained
more and more attention in the field of autoimmunity and secondary immunodeficiencies …