The purpose of this review is to discuss the achievements and perspectives regarding
rehabilitation of sensorimotor functions after spinal cord injury. In the first part we discuss …

Detailed pathophysiological findings of secondary damage phenomena after spinal cord
injury (SCI) as well as the identification of inhibitory and neurotrophic proteins have yielded …

In the United States alone, there are more than 200,000 individuals living with a chronic
spinal cord injury (SCI). Healthcare for these individuals creates a significant economic …

We investigated whether permeability transition-mediated release of mitochondrial
cytochrome c is a potential therapeutic target for treating acute spinal cord injury (SCI) …

Transplantation of exogenous cells is one approach to spinal cord repair that could
potentially enhance the growth and myelination of endogenous axons. Here, we asked …

Background Recent in vivo and in vitro studies in non-neuronal and neuronal tissues have
shown that different pathways of macrophage activation result in cells with different …

Demyelination contributes to the physiological and behavioral deficits after contusive spinal
cord injury (SCI). Therefore, remyelination may be an important strategy to facilitate repair …

Spinal cord injury (SCI) is one of the most common causes of death and disability. The
effective modulation of complicated microenvironment, regeneration of injured spinal cord …

Spinal cord trauma activates the immune system and elicits leukocyte recruitment to the site
of injury. This increase in immunological activity contributes to acute lesion expansion over a …

During the past few years, several approaches to spinal-cord repair have been successfully
established in animal models. For their use in trials of spinal-cord injury (SCI) in human …