Treatment of infantile spasms

EC Hancock, JP Osborne… - Cochrane Database of …, 2013 - cochranelibrary.com
Background Infantile spasms (West's Syndrome) is a syndrome that includes a peculiar type
of epileptic seizure—the spasms—and an electroencephalographic (EEG) abnormality often …

Efficacy and tolerability of the ketogenic diet versus high‐dose adrenocorticotropic hormone for infantile spasms: a single‐center parallel‐cohort randomized …

A Dressler, F Benninger, P Trimmel‐Schwahofer… - …, 2019 - Wiley Online Library
Objective To compare the efficacy and safety of the ketogenic diet (KD) with standard
adrenocorticotropic hormone (ACTH) treatment in infants with West syndrome. Methods In …

[HTML][HTML] Hormonal therapy for infantile spasms: a systematic review and meta-analysis

S Guang, L Mao, L Zhong, F Liu, Z Pan, F Yin… - Frontiers in …, 2022 - frontiersin.org
Objective The limitations of adrenocorticotrophic hormone (ACTH) treatment for infantile
spasms (ISs), such as high costs, limited availability, and adverse effects (AEs), make it …

Randomized, single-blind, parallel clinical trial on efficacy of oral prednisolone versus intramuscular corticotropin on immediate and continued spasm control in west …

J Wanigasinghe, C Arambepola, SS Ranganathan… - Pediatric …, 2015 - Elsevier
Objective A single-center, single-blind, parallel-group, randomized clinical trial was
performed to test the null hypothesis that adrenocorticotropic hormone is not superior to high …

Treatment of infantile spasms: report of the interdisciplinary guideline committee coordinated by the German-speaking society for neuropediatrics

D Tibussek, J Klepper, R Korinthenberg… - …, 2016 - thieme-connect.com
Objectives This report aims to define treatment goals, to summarize the evidence level (EL)
of different treatment options for infantile spasms (IS), both in terms of efficacy and adverse …

[HTML][HTML] Кортикостероидная терапия фармакорезистентных эпилепсий у детей

ЛВ Шалькевич, ГГ Шанько, ДА Кот - Международный …, 2014 - cyberleninka.ru
В работе проведен анализ факторов, влияющих на эффективность кортикостероидной
терапии резистентной эпилепсии вне рамок синдрома Веста у 108 детей в возрасте от …

Efficacy of high-dose ACTH versus low-dose ACTH in infantile spasms: a meta-analysis with direct and indirect comparison of randomized trials

L Zeng, R Luo, L Zhang - Journal of Pediatric Neurology, 2011 - content.iospress.com
To determine the influence of dose on the efficacy and safety of adrenocorticotropic
hormone (ACTH) for infantile spasms. We searched six relative databases. Randomized …

Adrenocorticotropic hormone and corticosteroids

F Vigevano, MR Cilio - The treatment of epilepsy, 2015 - Wiley Online Library
In 1958, it was discovered that adrenocorticotropic hormone (ACTH or corticotropin) was
efficacious in controlling seizures and improving abnormalities seen on …

[PDF][PDF] Therapie der Blitz-Nick-Salaam Epilepsie (West-Syndrom)

F Autor, B Schmitt - awmf.org
Therapie der Blitz-Nick-Salaam Epilepsie (West-Syndrom) Page 1 1 publiziert bei: AWMF-Register
Nr. 022/022 Klasse: S3 Therapie der Blitz-Nick-Salaam Epilepsie (West-Syndrom) S3 Leitlinie …

Review of West Syndrome: Concerns on Optimum Dose of Adrenocorticotrophic Hormone

JK Sahu, VK Vaddi, S Negi - Clinical drug investigation, 2018 - Springer
We read with interest the recently published article by D'Alonzo and colleagues [1]. We
congratulate them for presenting an exhaustive and lucid review of evidence-base on …