Allergic rhinitis: a clinical and pathophysiological overview

SM Nur Husna, HTT Tan, N Md Shukri… - Frontiers in …, 2022 - frontiersin.org
Allergic rhinitis (AR) represents a global health concern where it affects approximately 400
million people worldwide. The prevalence of AR has increased over the years along with …

Promising therapeutic targets for treatment of rheumatoid arthritis

J Huang, X Fu, X Chen, Z Li, Y Huang… - Frontiers in …, 2021 - frontiersin.org
Rheumatoid arthritis (RA) is a systemic poly-articular chronic autoimmune joint disease that
mainly damages the hands and feet, which affects 0.5% to 1.0% of the population …

Pathogenic role of immune cells in rheumatoid arthritis: implications in clinical treatment and biomarker development

HY Yap, SZY Tee, MMT Wong, SK Chow, SC Peh… - Cells, 2018 - mdpi.com
Rheumatoid arthritis (RA) is a chronic, autoimmune, systemic, inflammatory disorder that
affects synovial joints, both small and large joints, in a symmetric pattern. This disorder …

Flavonoids as cytokine modulators: a possible therapy for inflammation-related diseases

N Leyva-López, EP Gutierrez-Grijalva… - International journal of …, 2016 - mdpi.com
High levels of cytokines, such as interleukin (IL)-1β, tumor necrosis factor (TNF)-α and IL-6,
are associated with chronic diseases like rheumatoid arthritis, asthma, atherosclerosis …

Regulation of immune function by vitamin D and its use in diseases of immunity

AS Vanherwegen, C Gysemans… - … and Metabolism Clinics, 2017 - endo.theclinics.com
The immune system, innate and adaptive, is a highly evolved and complex network,
essential for promoting survival in an environment full of potential pathogens, while …

Intake of ω-3 polyunsaturated fatty acids in patients with rheumatoid arthritis: A systematic review and meta-analysis

A Gioxari, AC Kaliora, F Marantidou, DP Panagiotakos - Nutrition, 2018 - Elsevier
Objectives Rheumatoid arthritis (RA) is a chronic, autoimmune inflammatory disease of
multiple joints that puts the patient at high risk for developing cardiovascular diseases …

The role of flavonoids in autoimmune diseases: Therapeutic updates

KRR Rengasamy, H Khan, S Gowrishankar… - Pharmacology & …, 2019 - Elsevier
Flavonoids are natural polyphenolic compounds which are included in a panoply of drugs
and used to treat and/or manage human ailments such as metabolic, cardiovascular …

Photoacoustic image-guided biomimetic nanoparticles targeting rheumatoid arthritis

J Chen, S Zeng, Q Xue, Y Hong, L Liu… - Proceedings of the …, 2022 - National Acad Sciences
The high level of reactive oxygen species (ROS) in the rheumatoid arthritis (RA)
microenvironment (RAM) and its persistent inflammatory nature can promote damage to …

Re-examining the role of TNF in MS pathogenesis and therapy

D Fresegna, S Bullitta, A Musella, FR Rizzo, F De Vito… - Cells, 2020 - mdpi.com
Multiple sclerosis (MS) is a common neurological disorder of putative autoimmune origin.
Clinical and experimental studies delineate abnormal expression of specific cytokines over …

Level of inflammatory cytokines in rheumatoid arthritis patients: Correlation with 25-hydroxy vitamin D and reactive oxygen species

S Mateen, S Moin, S Shahzad, AQ Khan - PloS one, 2017 - journals.plos.org
Background Rheumatoid arthritis (RA) is an autoimmune inflammatory disorder. Reactive
oxygen species (ROS) and pro-inflammatory cytokines have been believed to be involved in …