Oral mucositis: the hidden side of cancer therapy

C Pulito, A Cristaudo, CL Porta, S Zapperi… - Journal of experimental …, 2020 - Springer
Inflammation response of epithelial mucosa to chemo-radiotherapy cytotoxic effects leads to
mucositis, a painful side effect of antineoplastic treatments. About 40% of the patients treated …

Radiotherapy toxicity

D De Ruysscher, G Niedermann, NG Burnet… - Nature Reviews …, 2019 - nature.com
Radiotherapy is used in> 50% of patients with cancer, both for curative and palliative
purposes. Radiotherapy uses ionizing radiation to target and kill tumour tissue, but normal …

Adult cancer pain, version 3.2019, NCCN clinical practice guidelines in oncology

RA Swarm, JA Paice, DL Anghelescu, M Are… - Journal of the National …, 2019 - jnccn.org
In recent years, the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for
Adult Cancer Pain have undergone substantial revisions focusing on the appropriate and …

New frontiers in the pathobiology and treatment of cancer regimen-related mucosal injury

M Cinausero, G Aprile, P Ermacora, D Basile… - Frontiers in …, 2017 - frontiersin.org
Mucositis is a common complication of chemotherapy, radiotherapy and targeted agents. It
often affects compliance to anticancer therapies as it frequently causes schedule delays …

The pathobiology of mucositis

ST Sonis - Nature Reviews Cancer, 2004 - nature.com
Oral and gastrointestinal mucositis is a toxicity of many forms of radiotherapy and
chemotherapy. It has a significant impact on health, quality of life and economic outcomes …

Perspectives on cancer therapy‐induced mucosal injury: pathogenesis, measurement, epidemiology, and consequences for patients

ST Sonis, LS Elting, D Keefe… - … Journal of the …, 2004 - Wiley Online Library
BACKGROUND A frequent complication of anticancer treatment, oral and gastrointestinal
(GI) mucositis, threatens the effectiveness of therapy because it leads to dose reductions …

Glutamine for amelioration of radiation and chemotherapy associated mucositis during cancer therapy

PM Anderson, RV Lalla - Nutrients, 2020 - mdpi.com
Glutamine is a major dietary amino acid that is both a fuel and nitrogen donor for healing
tissues damaged by chemotherapy and radiation. Evidence supports the benefit of oral …

Interventions for preventing oral mucositis for patients with cancer receiving treatment

HV Worthington, JE Clarkson, G Bryan… - Cochrane database …, 2011 - cochranelibrary.com
Background Treatment of cancer is increasingly more effective but is associated with short
and long term side effects. Oral side effects remain a major source of illness despite the use …

Management of oral mucositis in patients who have cancer

RV Lalla, ST Sonis, DE Peterson - Dental Clinics of North America, 2008 - Elsevier
Oral mucositis is a clinically important and sometimes dose-limiting complication of cancer
therapy. Mucositis lesions can be painful, affect nutrition and quality of life, and have a …

Clinical practice guidelines for the prevention and treatment of cancer therapy–induced oral and gastrointestinal mucositis

EB Rubenstein, DE Peterson… - … Journal of the …, 2004 - Wiley Online Library
BACKGROUND Oral and gastrointestinal (GI) mucositis can affect up to 100% of patients
undergoing high‐dose chemotherapy and hematopoietic stem cell transplantation, 80% of …