MatrisomeDB 2.0: 2023 updates to the ECM-protein knowledge database

X Shao, CD Gomez, N Kapoor… - Nucleic acids …, 2023 - academic.oup.com
The extracellular matrix (ECM) is a complex assembly of proteins that constitutes the scaffold
organizing cells, tissues, and organs. Over the past decade, mass-spectrometry-based …

[HTML][HTML] Identification and quantification of protein nitration sites in human coronary artery smooth muscle cells in the absence and presence of peroxynitrous acid …

S Xu, CY Chuang, CL Hawkins, P Hägglund… - Redox Biology, 2023 - Elsevier
Peroxynitrous acid/peroxynitrite (ONOOH/ONOO−) is a powerful oxidizing/nitrating system
formed at sites of inflammation, which can modify biological targets, and particularly …

Phosphorylation Sites of the Gastric Inhibitory Polypeptide Receptor (GIPR) Revealed by Trapped-Ion-Mobility Spectrometry Coupled to Time-of-Flight Mass …

KA Brown, RK Morris, SJ Eckhardt, Y Ge… - Journal of the …, 2023 - ACS Publications
The gastric inhibitory polypeptide receptor (GIPR), a G protein-coupled receptor (GPCR) that
regulates glucose metabolism and insulin secretion, is a target for the development of …

PrIntMap-R: An Online Application for Intraprotein Intensity and Peptide Visualization from Bottom-Up Proteomics

SD Weaver, CM DeRosa, SR Schultz… - Journal of Proteome …, 2023 - ACS Publications
Bottom-up proteomics (BUP) produces rich data, but visualization and analysis are time-
consuming and often require programming skills. Many tools analyze these data at the …

Exploring the phospho-landscape of NEK6 kinase: systematic annotation of phosphosites and their implications as biomarkers in carcinogenesis

D Sanjeev, S Mendon, M George, L John… - Journal of Proteins and …, 2024 - Springer
Abstract NIMA-related kinase 6 (NEK6) is a serine/threonine protein kinase known for its
ability to promote cell progression and is a promising therapeutic target in multiple cancers …

Matrimeres are systemic nanoscale mediators of tissue integrity and function

K Debnath, I Qayoom, S O'Donnell, J Ekiert, C Wang… - bioRxiv, 2024 - biorxiv.org
Tissue barriers must be rapidly restored after injury to promote regeneration. However, the
mechanism behind this process is unclear, particularly in cases where the underlying …

Learning tool of chemical molecules for healthcare students based on 3D visualizations, Large Language Models and Linked Open Data

ML Prieto, MF Gilsanz, E Puertas - Proceedings of the 2023 7th …, 2023 - dl.acm.org
This paper presents a software tool designed to assist healthcare students and teachers in
applying case-based learning methodologies for studying chemical compounds and their …