Abstract Serotonin (5-hydroxytryptamine, 5-HT) was one of the first neurotransmitters for
which a role in development was identified. Pharmacological and gene knockout studies …

The biogenic amines dopamine and serotonin are neurotransmitters and hormones, which
are mainly produced in the central nervous system and in the gastro-intestinal tract. They …

We have reviewed the scientific literature related to four diseases in which to serotonin (5-
HT) is involved in the etiology, herein named 5-HT-linked diseases, and whose prevalence …

Bipolar disorder (BD) is a severe and debilitating illness that affects 1–2% of the population
worldwide. BD is characterized by recurrent and extreme mood swings, including …

Novel molecular pathways obligatory for bone health are being rapidly identified. One
pathway recently revealed involves gut-derived 5-hydroxytryptamine (5-HT) mediation of the …

Sertraline (SER) is one of the most frequently detected antidepressant drugs in aquatic
environments. However, knowledge regarding SER-induced behavioral alterations in fish is …

Serotonin, a highly pro-inflammatory molecule released by activated platelets, is formed by
tryptophan. Tryptophan is also needed in the production of kynurenine, a process mediated …

Heart valves exhibit a highly-conserved stratified structure exquisitely designed to counter
biomechanical forces delivered over a lifetime. Heart valve structure and competence is …

Objectives: Describe the clinical presentation of serotonin syndrome. Summarize the Hunter
criteria and how they are used to diagnose serotonin syndrome. Outline the treatment and …

Mast cells play an important role in the body defense against allergens, pathogens, and
parasites by participating in inflammation development. However, there is evidence for their …