The aim of this study was to evaluate the effects of sarpogrelate hydrochloride (SH), a
selective serotonin 2A receptor antagonist, on diabetic nephropathy in a type 2 diabetes …

Due to ineffective wastewater treatment technologies, pharmaceuticals such as the selective
serotonin reuptake inhibitors (SSRIs)—a common class of antidepressants which inhibit the …

Background: It is well established that the serotonergic system (SS) plays important roles in
the pathogenesis of cardiovascular diseases. However, the impact of serotonin and its inter …

Abstract Introduction Serotonin (5-hydroxytryptamine [5-HT]) has several biological
functions. In different species, excessive 5-HT has been linked to valvular lesions, similar to …

Carcinoid tumors (CT) are among the least studied tumors. It is a relatively rare and slow-
growing tumor with good survival in its primary form. However, metastatic carcinoid tumor …

Pulmonary hypertension syndrome (PHS; ascites) in fast growing meat-type chickens
(broilers) is characterized by the onset of idiopathic pulmonary arterial hypertension (IPAH) …

Background Serotonin transporter knockout mice have been a powerful tool in
understanding the role played by the serotonin transporter in modulating physiological …

Diabetes is a major risk factor for the development of heart failure. One of the hallmarks of
diabetes is insulin resistance associated with hyperinsulinemia. The literature shows that …

Bereits in den 1960er-Jahren wurde eine Beteiligung von Serotonin (5-Hydroxytryptamin, 5-
HT) an psychischen Krankheiten erkannt, was durch unterschiedlichste Forschungsansätze …

The use of 'agonist therapy'for cocaine and methamphetamine addiction involves
administration of stimulant-like medications (eg monoamine releasers) to reduce withdrawal …