Mechanisms underlying increased serotonin-induced contraction in carotid arteries from chronic type 2 diabetic Goto-Kakizaki rats

T Matsumoto, S Watanabe, K Taguchi… - Pharmacological …, 2014 - Elsevier
Abstract Serotonin (5-hydroxytryptamine; 5-HT) plays important roles in the cardiovascular
system; however, the relationship between 5-HT-induced vasocontraction and the arterial 5 …

Beneficial effects of trimetazidine on expression of serotonin and serotonin transporter in rats with myocardial infarction and depression

M Liu, W Wei, CR Stone, L Zhang, G Tian… - Neuropsychiatric …, 2018 - Taylor & Francis
Background Trimetazidine is an anti-ischemic drug that can inhibit platelet aggregation and
regulate serotonin (5-hydroxytryptamine [5-HT]) release. The purpose of this study was to …

Effects of MDMA and related analogs on plasma 5-HT: relevance to 5-HT transporters in blood and brain

S Yubero-Lahoz, MA Ayestas Jr, BE Blough… - European journal of …, 2012 - Elsevier
(±)-3, 4-Methylenedioxymethamphetamine (MDMA) is an illicit drug that evokes transporter-
mediated release of serotonin (5-HT) in the brain. 5-HT transporter (SERT) proteins are also …

[HTML][HTML] Neuroimmune modulation by tryptophan derivatives in neurological and inflammatory disorders

T Kondo, Y Okada, S Shizuya, N Yamaguchi… - European Journal of …, 2024 - Elsevier
The nervous and immune systems are highly developed, and each performs specialized
physiological functions. However, they work together, and their dysfunction is associated …

Serotonin transmembrane transporter is down-regulated in late-stage canine degenerative mitral valve disease

SM Scruggs, S Disatian, EC Orton - Journal of Veterinary Cardiology, 2010 - Elsevier
OBJECTIVE: To compare expression of the serotonin transmembrane transporter (SERT) in
normal, early-stage degenerative, and late-stage degenerative canine mitral valve disease …

Could serotonin be a potential marker for hepatocellular carcinoma? A prospective single-center observational study

A Abdel-Razik, R Elhelaly, R Elzehery… - European journal of …, 2016 - journals.lww.com
Background Hepatocellular carcinoma (HCC) is the third most common cause of cancer
mortality among men worldwide. Serotonin is a biogenic amine, which may be involved in …

[HTML][HTML] Investigation of Genes and Proteins Expression Associating Serotonin Signaling Pathway in Lung and Pulmonary Artery Tissues of Dogs with Pulmonary …

N Tangmahakul, S Sakarin, S Techangamsuwan… - Veterinary …, 2022 - mdpi.com
Simple Summary Pulmonary hypertension is an unusual elevation of the blood pressure in
pulmonary circulation. In dogs, pulmonary hypertension is commonly occurred as a …

Serotonin (5-HT) in veins: not all in vain

AE Linder, W Ni, JL Diaz, T Szasz, R Burnett… - … of Pharmacology and …, 2007 - ASPET
The circulatory system consists of veins and arteries. Compared with arteries, veins have
been neglected in cardiovascular research. Although veins are significantly less muscular …

Serotonin transporter gene deficiency is associated with sudden death of newborn mice through activation of TGF-β1 signalling

LM Pavone, A Spina, S Rea, D Santoro… - Journal of molecular and …, 2009 - Elsevier
The serotonin transporter (SERT) gene has been proposed as a candidate gene
responsible for the sudden infant death syndrome (SIDS). In this study, for the first time we …

[HTML][HTML] Serotonin—A Driver of Progressive Heart Valve Disease

H Waldum, A Wahba - Frontiers in Cardiovascular Medicine, 2022 - frontiersin.org
It is well known that some serotoninergic drugs and neuroendocrine tumors producing
serotonin (5-HT) may induce valvular heart disease by stimulation of proliferation of valvular …