Ischemic heart disease still represents a large burden on individuals and health care
resources worldwide. By conventions, it is equated with atherosclerotic plaque due to flow …

Many patients with chest pain undergoing coronary angiography do not show significant
obstructive coronary lesions. A substantial proportion of these patients have abnormalities in …

Surveys and registries are needed to verify that real-life daily practice is in keeping with what
is recommended in the guidelines, thus completing the loop between clinical research …

Acute coronary syndromes (ACS) are a comprehensive disease concept characterized by
acute myocardial ischemia caused by disruption of coronary artery plaque and consequent …

ST-segment elevation myocardial infarction (STEMI) is the most acute manifestation of
coronary artery disease and is associated with great morbidity and mortality. A complete …

Background We compared the clinical characteristics and outcomes of young patients with
myocardial infarction with nonobstructive coronary arteries (MINOCA) versus obstructive …

The incidence of ST segment elevation myocardial infarction (STEMI) has decreased over
the last two decades in developed countries, but mortality from STEMI despite widespread …

In recent years, it has become apparent that coronary microvascular dysfunction plays a
pivotal pathogenic role in angina pectoris. Functional and structural mechanisms can affect …

Although myocardial ischaemia usually manifests as a consequence of atherosclerosis-
dependent obstructive epicardial coronary artery disease, a significant percentage of …

Aims Microvascular obstruction (MVO) is the underlying cause for the no-reflow
phenomenon in ST-segment elevation myocardial infarction (STEMI). The association …