Platinum-complexes represent some of the most successful groups of clinically used
anticancer drugs. Their mechanism of action relies on the formation of stable DNA adducts …

Schneidewerkzeug: Zn (OTf) 2 ist ein effizienter Katalysator für die selektive Spaltung von
Amiden mit β‐Hydroxyethylgruppe am Stickstoffatom. Der Mechanismus umfasst eine N, O …

Platinum-based agents continue to be a mainstay as components of many standard
chemotherapy regimens. To improve the tolerability and efficacy of these important oncology …

We report for the first time on the selective hydrolysis of a polypeptide system by a metal-
substituted polyoxometalate (POM). Oxidized insulin chain B, a 30 amino acid polypeptide …

CeO2 has been found to promote ester forming alcoholysis reactions of tertiary amides. The
present catalytic system is operationally simple, recyclable, and it does not require additives …

In this study, mechanisms of hydrolysis of all four chemically diverse cleavage sites of
human serum albumin (HSA) by [Zr (OH)(PW11O39)] 4−(ZrK) have been investigated using …

In the present DFT study, mechanisms of peptide hydrolysis by Co (III)-and Cu (II)-containing
complexes of 1, 4, 7, 10-tetraazacyclododecane (cyclen), 1-Co and 1-Cu, respectively, and 1 …

Alcoholysis of amides on the CeO 2 surface is investigated from density functional theory
(DFT) computations, in situ FT-IR spectroscopy, and catalytic studies. The …

In this DFT study, activities of 11 different N2O4, N2O3, and NO2 core containing Zr (IV)
complexes, 4, 13-diaza-18-crown-6 (I′ N2O4), 1, 4, 10-trioxa-7, 13-diazacyclopentadecane …

In this study, mechanistic insights into the hydrolysis of an extremely stable tertiary peptide
bond (Ser–Pro) in the Ser-Pro-Phe sequence by an artificial enzyme, metal (Pd2+, Co2+, or …