RNA-binding proteins (RBPs) can regulate gene expression through post-transcriptionally
influencing all manner of RNA biology, including alternative splicing (AS), polyadenylation …

Simple Summary Chronic hyperglycemia manifests in a variety of different micro-and
macrovascular disorders such as diabetes mellitus and cardiovascular disease and has …

Sunitinib is an antiangiogenic therapy given as a first-line treatment for renal cell carcinoma
(RCC). While treatment improves progression-free survival, most patients relapse. We …

Human ageing is a complex and integrated gradual deterioration of cellular processes.
There are nine major hallmarks of ageing, that include changes in DNA repair and DNA …

Cytochrome c (Cc) is a protein that functions as an electron carrier in the mitochondrial
respiratory chain. However, Cc has moonlighting roles outside mitochondria driving the …

Diabetic retinopathy (DR) is a vision-impairing complication of diabetes, damaging the
retinal microcirculatory system. Overexpression of VEGF (vascular endothelial growth factor) …

Long non-coding RNAs (lncRNAs) have recently been identified as critical regulators in
tumor initiation and development. However, the function of lncRNAs in human …

The heat shock response (HSR) is a crucial biochemical pathway that orchestrates the
resolution of inflammation, primarily under proteotoxic stress conditions. This process hinges …

The RNA-binding protein (RBP) HuR is one of the most widely studied regulators of the
eukaryotic posttranscriptional gene expression and it plays a physiological role in mediating …

Cancer is a significant health hazard of the 21st century, and GLOBOCAN predicts
increasing cancer incidence in the coming decades. Though several conventional treatment …