Pancreatic islet transplantation in humans: recent progress and future directions

MR Rickels, RP Robertson - Endocrine reviews, 2019 - academic.oup.com
Pancreatic islet transplantation has become an established approach to β-cell replacement
therapy for the treatment of insulin-deficient diabetes. Recent progress in techniques for islet …

Human pluripotent stem-cell-derived islets ameliorate diabetes in non-human primates

Y Du, Z Liang, S Wang, D Sun, X Wang, SY Liew… - Nature medicine, 2022 - nature.com
Human pluripotent stem-cell-derived islets (hPSC-islets) are a promising cell resource for
diabetes treatment,. However, this therapeutic strategy has not been systematically …

Assessment of risks and benefits of beta cell replacement versus automated insulin delivery systems for type 1 diabetes

P Senior, A Lam, K Farnsworth, B Perkins… - Current Diabetes …, 2020 - Springer
Abstract Purpose of Review Current approaches to insulin replacement in type 1 diabetes
are unable to achieve optimal levels of glycemic control without substantial risk of …

Long‐term outcome of islet transplantation on insulin‐dependent diabetes mellitus: an observational cohort study

T Nakamura, J Fujikura, T Anazawa… - Journal of Diabetes …, 2020 - Wiley Online Library
Abstract Aims/Introduction To investigate the long‐term efficacy and safety of islet
transplantation (ITx) compared with multiple daily injections (MDI) or continuous …

Anti-inflammatory approach with early double cytokine blockade (IL-1β and TNF-α) is safe and facilitates engraftment in islet allotransplantation

N Onaca, M Takita, MF Levy… - Transplantation Direct, 2020 - journals.lww.com
Background. The approach to reducing nonspecific inflammation after islet
allotransplantation has been designed to improve engraftment, typically using 1 agent. We …

[PDF][PDF] Histopathology of human islet cell implants: Contribution to insights in their function

F VAN HULLE - 2023 - cris.vub.be
The presented work has been supported by grants from the European Commission (FP7
241883 and H2020 681070), Juvenile Diabetes Research Foundation (JDRF)(17-2013-296 …

Современное состояние проблемы аллотрансплантации клеток Лангерганса (достижения и перспективы)

АВ Алекберзаде, НН Крылов, З Аджун… - Хирургия. Журнал им …, 2018 - elibrary.ru
Диабет 1-го типа (СД1) возникает в результате аутоиммунного повреждения островков
Лангерганса поджелудочной железы, сопровождаемого аутоиммунным разрушением β …

[PDF][PDF] Lvads: A Two-Sided Dilemma when Buying Time for Heart Transplantation. SOJ Surgery 4 (1): 1-3

M Binks - Lvads: A Two-Sided Dilemma when Buying …, 2017 - pdfs.semanticscholar.org
Our ageing population is experiencing an unprecedented level of heart disease. Medical
therapy is often inadequate in those with endstage heart failure. Mechanical cardiac support …