Curcumin, a yellow pigment in the Indian spice Turmeric (Curcuma longa), which is
chemically known as diferuloylmethane, was first isolated exactly two centuries ago in 1815 …

The last decade has seen an unprecedented rise in the prevalence of chronic diseases
worldwide. Different mono‐targeted approaches have been devised to treat these multigenic …

An association of melatonin levels with age disease initiation of autoimmune diseases and
pineal calcification was reported while an inverse association between melatonin levels and …

MicroRNAs (miRNAs) are small endogenous RNAs that regulate gene expression post-
transcriptionally by targeting either the 3′ untranslated or coding regions of genes. They …

Recent research has highlighted the importance of the two-way interaction between the
nervous and immune systems. This interaction is particularly important in the bowel because …

The human gut microbiome has a considerable impact on host health. The long list of
microbiome-related health disorders raises the question of what in fact determines …

Abstract Inflammatory Bowel diseases (IBDs) constitute a complex panel of disorders
characterized with chronic inflammation affecting the alimentary canal along with extra …

In spite of the well-established histopathological phenotyping of IBD-associated
preneoplastic and neoplastic lesions, their molecular landscape remains to be fully …

Genetic research has shaped the inflammatory bowel disease (IBD) landscape identifying
nearly two hundred risk loci. Nonetheless, the identified variants rendered only a partial …

Inflammatory bowel disease (IBD) is a chronic inflammatory condition of the gastrointestinal
tract with an incompletely understood pathogenesis. Long-standing colitis is associated with …