[PDF][PDF] NLRP3 炎性小体在慢性心力衰竭中的作用与机制
王敢, 钟江华 - 临床心血管病杂志, 2023 - en.whuhzzs.com
慢性心力衰竭(chronicheartfailure, CHF) 是各类心血管疾病的终末期阶段. CHF
的治疗方案近年虽不断完善, 但仍有较高的死亡率与住院率, 给患者及家庭带来了巨大的医疗 …
的治疗方案近年虽不断完善, 但仍有较高的死亡率与住院率, 给患者及家庭带来了巨大的医疗 …
IL-1 signaling pathway, an important target for inflammation surrounding in myocardial infarction
J Huang, W Kuang, Z Zhou - Inflammopharmacology, 2024 - Springer
Acute myocardial infarction is an important cardiovascular disease worldwide. Although the
mortality rate of myocardial infarction (MI) has improved dramatically in recent years due to …
mortality rate of myocardial infarction (MI) has improved dramatically in recent years due to …
Clinical and pharmacological implications of time to treatment with interleukin-1 blockade in ST-segment elevation myocardial infarction
Interleukin-1 (IL-1) blockade with anakinra given within 12 hours from reperfusion has been
shown to reduce the inflammatory response as well as prevent heart failure (HF) events in …
shown to reduce the inflammatory response as well as prevent heart failure (HF) events in …
Change in Eosinophil Count in Patients with Heart Failure Treated with Anakinra
Background: Interleukin-1 blockade with anakinra leads to a transient increase in eosinophil
blood count (eosinophils) in patients with acute myocardial infarction. We aimed to …
blood count (eosinophils) in patients with acute myocardial infarction. We aimed to …
IL-1β is not critical to chronic heart dysfunction in mice with Chagas disease
CV Sousa Oliveira, O Moreno-Loaiza… - Frontiers in …, 2022 - frontiersin.org
Long after Trypanosoma cruzi infection, 40% of individuals develop a progressive chronic
chagasic cardiomyopathy (CCC), with systolic dysfunction and arrhythmias. Since we …
chagasic cardiomyopathy (CCC), with systolic dysfunction and arrhythmias. Since we …
Targeting Inflammation After Myocardial Infarction—Another Piece of the Puzzle
Coronary artery disease (CAD) is one of the major causes of morbidity and mortality in the
western world. Despite major improvements in treatment in the acute phase, myocardial …
western world. Despite major improvements in treatment in the acute phase, myocardial …
Heart failure in chronic infectious and inflammatory conditions: mechanistic insights from clinical heterogeneity
N Beydoun, MJ Feinstein - Current heart failure reports, 2022 - Springer
Abstract Purpose of Review The balance between inflammation and its resolution plays an
important and increasingly appreciated role in heart failure (HF) pathogenesis. In humans …
important and increasingly appreciated role in heart failure (HF) pathogenesis. In humans …
Interleukin-1 and Eosinophils in Heart Failure
M Golino - 2023 - irinsubria.uninsubria.it
Background. Anakinra, an IL-1 inhibitor, temporarily increases eosinophil blood levels in
patients with acute myocardial infarction and reduces heart failure (HF) events. Anakinra is …
patients with acute myocardial infarction and reduces heart failure (HF) events. Anakinra is …
Joint Application of Multiple Inflammatory Cytokines in Development of Heart Failure
M Yu, Q Zhang, J Zhu, L Xu, L Chen, K Zheng - 2023 - researchsquare.com
Background Heart failure is a serious heart ailment that affects millions of people globally in
terms of their quality of life and general health. In the development and pathophysiology of …
terms of their quality of life and general health. In the development and pathophysiology of …
The role and mechanism of NLRP3 inflammasome in chronic heart failure
W Gan, Z Jianghua - J Clin Cardiol, 2023 - lcxxgen.whuhzzs.com
Chronic heart failure (CHF) is the terminal stage of cardiovascular disease. Although the
treatment of CHF has been continuously improved in recent years, there are still high …
treatment of CHF has been continuously improved in recent years, there are still high …