[HTML][HTML] Hypoxia signaling in human health and diseases: implications and prospects for therapeutics

Z Luo, M Tian, G Yang, Q Tan, Y Chen, G Li… - Signal transduction and …, 2022 - nature.com
Molecular oxygen (O2) is essential for most biological reactions in mammalian cells. When
the intracellular oxygen content decreases, it is called hypoxia. The process of hypoxia is …

[HTML][HTML] Obesity and obesity-induced inflammatory disease contribute to atherosclerosis: a review of the pathophysiology and treatment of obesity

RJ Henning - American journal of cardiovascular disease, 2021 - ncbi.nlm.nih.gov
Two billion people worldwide older than 18 years of age, or approximately 30% of the world
population, are overweight or obese. In addition, more than 43 million children under the …

[HTML][HTML] Diabetes and sarcopenic obesity: pathogenesis, diagnosis, and treatments

M Wang, Y Tan, Y Shi, X Wang, Z Liao… - Frontiers in …, 2020 - frontiersin.org
Sarcopenic obesity and diabetes are two increasing health problems worldwide, which both
share many common risk factors, such as aging, and general obesity. The pathogenesis of …

[HTML][HTML] Insights into SGLT2 inhibitor treatment of diabetic cardiomyopathy: focus on the mechanisms

K Huang, X Luo, B Liao, G Li, J Feng - Cardiovascular Diabetology, 2023 - Springer
Among the complications of diabetes, cardiovascular events and cardiac insufficiency are
considered two of the most important causes of death. Experimental and clinical evidence …

[HTML][HTML] NLRP3 inflammasome at the interface of inflammation, endothelial dysfunction, and type 2 diabetes

IM Gora, A Ciechanowska, P Ladyzynski - Cells, 2021 - mdpi.com
Type 2 diabetes mellitus (T2DM), accounting for 90–95% cases of diabetes, is characterized
by chronic inflammation. The mechanisms that control inflammation activation in T2DM are …

[HTML][HTML] A role for advanced glycation end products in molecular ageing

K Zgutka, M Tkacz, P Tomasiak… - International journal of …, 2023 - mdpi.com
Ageing is a composite process that involves numerous changes at the cellular, tissue, organ
and whole-body levels. These changes result in decreased functioning of the organism and …

[PDF][PDF] QANDLI DIABET 2 TUR VA YURAK QON TOMIR KASALLIKLARINING BEMOLARDA BIRGALIKDA KECHISHI

EG Toxirovna - … НАУКА И ИННОВАЦИОННЫЕ ИДЕИ В МИРЕ, 2024 - newjournal.org
Annotatsiya: Qandli diabet-bu metabolik sindrom dunyoning deyarli barcha mamlakatlarida,
xususan, rivojlanayotgan davlatlarni tashvishga solmoqda. Turmush tarzi va genetik …

Three months of combination therapy with nano‐curcumin reduces the inflammation and lipoprotein (a) in type 2 diabetic patients with mild to moderate coronary …

M Dastani, HR Rahimi, VR Askari, MR Jaafari… - Biofactors, 2023 - Wiley Online Library
Diabetes is one of the most common chronic diseases worldwide. Systemic inflammation
(high‐sensitivity C‐reactive protein (hs‐CRP)) and lipid metabolism disruption (lipoprotein …

[HTML][HTML] The Wnt signaling pathway in diabetic nephropathy

H Wang, R Zhang, X Wu, Y Chen, W Ji… - Frontiers in Cell and …, 2022 - frontiersin.org
Diabetic nephropathy (DN) is a serious kidney-related complication of both type 1 and type 2
diabetes mellitus (T1DM, T2DM) and the second major cause of end-stage kidney disease …

[HTML][HTML] Inflammation as a precursor of atherothrombosis, diabetes and early vascular aging

E Barbu, MR Popescu, AC Popescu… - International Journal of …, 2022 - mdpi.com
Vascular disease was for a long time considered a disease of the old age, but it is becoming
increasingly clear that a cumulus of factors can cause early vascular aging (EVA) …