Possible roles of glycosphingolipids in lipid rafts

K Kasahara, Y Sanai - Biophysical Chemistry, 1999 - Elsevier
Recent studies have suggested that glycosphingolipid (GSL)-cholesterol microdomains in
cell membranes may function as platforms for the attachment of lipid-modified proteins, such …

Silencing of membrane-associated sialidase Neu3 diminishes apoptosis resistance and triggers megakaryocytic differentiation of chronic myeloid leukemic cells K562 …

C Tringali, B Lupo, F Cirillo, N Papini… - Cell Death & …, 2009 - nature.com
In chronic myeloid leukemia K562 cells, differentiation is also blocked because of low levels
of ganglioside GM3, derived by the high expression of sialidase Neu3 active on GM3. In this …

Reaction mechanism underlying CMP-N-acetylneuraminic acid hydroxylation in mouse liver: Formation of a ternary complex of cytochrome b5, CMP-N …

H Takematsu, T Kawano, S Koyama… - The Journal of …, 1994 - jstage.jst.go.jp
We have proposed that CMP-N-acetylneuraminic acid (CMP-NeuAc) hydroxylation is
mediated by an electron transport system consisting of cytochrome b5 (b5), b5 reducing …

Ganglioside GM3 inhibits proliferation and invasion of glioma

Y Fujimoto, S Izumoto, T Suzuki, M Kinoshita… - Journal of neuro …, 2005 - Springer
GM3, the simplest ganglioside, modulates cell adhesion, proliferation and differentiation in
the central nervous system and exogenously added GM3 regulates cell–cell and cell …

Ganglioside GM3 inhibits the proliferation of cultured keratinocytes

AS Paller, SL Arnsmeier, M Alvarez-Franco… - Journal of investigative …, 1993 - Elsevier
Ganglioside G M3 is the predominant ganglioside of keratinocyte membranes. It has been
proposed in other cell types that G M3 may participate in the regulation of cell proliferation …

[HTML][HTML] The missing link-likely pathogenetic role of GM3 and other gangliosides in the development of diabetic nephropathy

I Vukovic, J Bozic, A Markotic, S Ljubicic… - Kidney and Blood …, 2015 - karger.com
Despite scientific advances, diabetic nephropathy remains both a therapeutical challenge,
and one of the major diabetic complications. Chemical structure of gangliosides, the most …

[HTML][HTML] A microtubule-associated protein specific to differentiated neuroblastoma cells.

JB Olmsted, HD Lyon - Journal of Biological Chemistry, 1981 - Elsevier
A modified procedure is reported that enables microtubule assembly to occur in extracts of
differentiated neuroblastoma cells. Of the proteins that co-assemble through five successive …

3′-sialyllactose targets cell surface protein, SIGLEC-3, and induces megakaryocyte differentiation and apoptosis by lipid raft-dependent endocytosis

SH Ha, CH Kwak, JY Park, F Abekura, YC Lee… - Glycoconjugate …, 2020 - Springer
sialyllactose is one of the abundant components in human milk oligosaccharides (HMOs)
that protect infants from various viral infections in early stages of immune system …

[HTML][HTML] Molecular characterization of membrane type and ganglioside-specific sialidase (Neu3) expressed in E. coli

KT Ha, YC Lee, SH Cho, JK Kim, CH Kim - Molecules and cells, 2004 - Elsevier
Endogenous expression of human membrane type ganglioside sialidase (Neu3) was
examined in various cell lines including NB-1, U87MG, SK-MEL-2, SK-N-MC, HepG2 …

Sugar-induced conformational changes in boronic acid-appended poly (L-and D-lysine) s and sugar-controlled orientation of a cyanine dye on the polymers

T Kimura, S Arimori, M Takeuchi, T Nagasaki… - Journal of the …, 1995 - pubs.rsc.org
Poly (L-and D-lysine) s have been modified with para-or meta-phenylboronic acid
derivatives which act as sugar-binding sites (L-1 and D-1 for the para-isomer and L-2 for the …