A new assay method for glycosphingolipid glycosyl-transferase activities was developed
using a 96-well filtration plate of a MultiScreen assay system. An acceptor glycosphingolipid …

We have designed and synthesized of carbohydrate-binding peptides, gramicidin S
analogues. Asn/Asp/Gln and Trp residues in the peptides were employed as the binding …

The mechanism of interleukin-3 (IL-3) independent cell growth and of IL-3-associated
ganglioside expression was analysed using the IL-3 dependent murine myelogenous …

The functional studies of glycosphingolipids in hematology and immunology fields have
been discussed in this review. First,(1) Glycolipid antigens known as cell surface …

N-glycolylneuraminic acid (Neu5Gc) is one of the two most common forms of sialic acids
present in glycoproteins and glycolipids of mammalian tissues. It is synthesized from the …

Abstract So-called'de-differentiation'of malignant tumors is not identical with'retro-
differentiation'of normal cells, although induction of differentiation of tumor cells seems to be …

Immune cells, which are derived from bone marrow (BM), are differentiated into each of
finally differentiated terminal cell to act as functional self-defense system. This course of cell …

Identifying mechanisms underlying the synergistic pathological interaction between stroke
and Alzheimer's disease (AD) can effectively guide future therapeutic strategies for these …

Рассмотрены метаболизм, топология и возможные механизмы регуляции клеточного
содержания ганглиозида GM3. Обсуждаются биологические функции ганглиозида GM3 …

Sialidases or neuraminidases (EC 3.2. 1.18; N-acylneuraminyl glycohydrolases) are a family
of exo-glycosidases that catalyze the hydrolytic cleavage of non-reducing sialic acid …