Recent advances in imaging and tracing technology provide increasingly detailed
reconstructions of brain connectomes. Concomitant analytic advances enable rigorous …

Neurodegenerative diseases are the most common cause of dementia. Although their
underlying molecular pathologies have been identified, there is substantial heterogeneity in …

Numerous brain disorders demonstrate structural brain abnormalities, which are thought to
arise from molecular perturbations or connectome miswiring. The unique and shared …

The brain is a network of interleaved neural circuits. In modern connectomics, brain
connectivity is typically encoded as a network of nodes and edges, abstracting away the rich …

The brain is composed of disparate neural populations that communicate and interact with
one another. Although fiber bundles, similarities in molecular architecture, and synchronized …

Neurotransmitter receptors modulate signaling between neurons. Thus, neurotransmitter
receptors and transporters play a key role in shaping brain function. Due to the lack of …

There is extensive synaptic loss from frontotemporal lobar degeneration, in preclinical
models and human in vivo and post mortem studies. Understanding the consequences of …

Schizophrenia is a prototypical network disorder with widespread brain-morphological
alterations, yet it remains unclear whether these distributed alterations robustly reflect the …

The identification of a neurodegenerative disorder's distributed pattern of atrophy—or
atrophy 'signature'—can lend insights into the cortical networks that degenerate in …

INTRODUCTION The three clinical variants of frontotemporal dementia (behavioral variant
[bvFTD], semantic dementia, and progressive non‐fluent aphasia [PNFA]) are likely to …