Cirrhosis is defined as the histological development of regenerative nodules surrounded by
fibrous bands in response to chronic liver injury, which leads to portal hypertension and end …

Aims The Korean Association for the Study of the Liver (KASL) Practice Guidelines for
Management of Hepatitis C were first established in 2004, and revised in 2013, when direct …

These are the first World Health Organization (WHO) guidelines for the prevention care and
treatment of persons living with CHB infection and complement similar recent published …

These guidelines have been written to assist physicians and other health care providers in
the recognition, diagnosis, and management of patients chronically infected with the …

Background Entecavir is a potent and selective guanosine analogue with significant activity
against hepatitis B virus (HBV). Methods In this phase 3, double-blind trial, we randomly …

Patients with chronic hepatitis B virus (HBV) infection who develop antiviral resistance lose
benefits of therapy and may be predisposed to further resistance. Entecavir (ETV) resistance …

Substantial advances have been made in the treatment of chronic hepatitis B in the past
decade. Approved treatments for chronic hepatitis B include 2 formulations of interferon and …

It is estimated conservatively that more than one third of the world's population has been
infected with the hepatitis B virus (HBV) and that there are 350 million people with chronic …

More than 360 million persons worldwide (6% of the world population) are chronically
infected by the hepatitis B virus (HBV). Although the incidence of HBV infection has …

Background & Aims: Lamivudine treatment is associated with frequent development of
resistant hepatitis B virus (HBV) and loss of treatment benefit. In preclinical and phase II …