Nuclear factor erythroid 2-related factor 2 (Nrf2) is a vital transcription factor and its induction
is of significant importance for protecting against oxidative damage. Increased levels of …

Pancreatic cancer is one of the most common causes of cancer death in the world due to the
lack of early symptoms, metastasis occurrence and chemoresistance. Therefore, early …

Chemoresistance including intrinsic and acquired anticancer drug resistance continues to
be a primary hindrance towards curative cancer treatment. Therefore, deciphering the …

Mitochondrial DNA (mtDNA) has been identified as a significant genetic biomarker in
disease, cancer and evolution. Mitochondria function as modulators for regulating cellular …

Long non-coding RNAs (lncRNAs) have been demonstrated to influence the
chemoresistance of colorectal cancer (CRC). Therefore, the study is designed to investigate …

The balance between pro-and antioxidant molecules has been established as an important
driving force in the pathogenesis of cardiovascular disease. Chronic heart failure is …

Esophageal cancer (EC) is one of the most common malignancies of the digestive system
and has a high morbidity and mortality worldwide. Chemotherapy in combination with …

Simple Summary Multidrug resistance (MDR) is a major cause of breast cancer (BC)
chemotherapy failure. Long noncoding RNAs (lncRNAs) have been shown closely related to …

Ferroptosis, a relatively recently discovered type of cell death that is iron dependent and
nonapoptotic, is involved in the accumulation of lipid reactive oxygen species (ROS), and …

Despite the recent advances in cancer therapy, cancer chemoresistance looms large along
with radioresistance, a major challenge in dire need of thorough and minute investigation …