Xinmailong injection on left ventricular remodeling and inflammatory mediators in patients with CHF: a systematic review and meta-analysis

X Han, X Chen, Y Liu, J Yang, W Nie… - Frontiers in …, 2024 - frontiersin.org
Background: Chronic heart failure (CHF) is a prevalent and highly challenging
cardiovascular disease associated with high mortality rates. The occurrence and …

Boldine prevents the inflammatory response of cardiac fibroblasts induced by SGK1-NFκB signaling pathway activation

M Catalán, F González-Herrera, JD Maya, O Lorenzo… - Cellular …, 2024 - Elsevier
Cardiac fibroblasts (CF) are mesenchymal-type cells responsible for maintaining the
homeostasis of the heart's extracellular matrix (ECM). Their dysfunction leads to excessive …

[HTML][HTML] Transcriptomic Analysis of Arachidonic Acid Pathway Genes Provides Mechanistic Insight into Multi-Organ Inflammatory and Vascular Diseases

V Aradhyula, JD Breidenbach, BZ Khatib-Shahidi… - Genes, 2024 - mdpi.com
Arachidonic acid (AA) metabolites have been associated with several diseases across
various organ systems, including the cardiovascular, pulmonary, and renal systems. Lipid …

Guideline-Optimised Treatment in Heart Failure—Do Higher Doses Reduce Systemic Inflammation More Significantly?

AM Arvunescu, RF Ionescu, SI Dumitrescu… - Journal of Clinical …, 2024 - mdpi.com
Background: Chronic inflammation is a constant phenomenon which accompanies the heart
failure pathophysiology. In all phenotypes of heart failure, irrespective of the ejection …