Heritable variation in gene expression is common within and between species. This
variation arises from mutations that alter the form or function of molecular gene regulatory …

The nonsense‐mediated mRNA decay pathway selects and degrades its targets using a
dense network of RNA‐protein and protein–protein interactions. Together, these interactions …

Gene-expression programs define shared and species-specific phenotypes, but their
evolution remains largely uncharacterized beyond the transcriptome layer. Here we report …

The genetic basis of most traits is highly polygenic and dominated by non-coding alleles. It is
widely assumed that such alleles exert small regulatory effects on the expression of cis …

Kaposi's sarcoma-associated herpesvirus (KSHV), also known as human herpesvirus-8
(HHV-8), is etiologically linked to the development of Kaposi's sarcoma, primary effusion …

Processing and maturation of precursor RNA species is coupled to RNA polymerase II
transcription. Co‐transcriptional RNA processing helps to ensure efficient and proper …

Abstract Background The Ccr4-Not complex is mostly known as the major eukaryotic
deadenylase. However, several studies have uncovered roles of the complex, in particular of …

Post-translational and epigenetic regulation are important mechanisms controlling functions
of genes and proteins. Although the “classic” estrogen receptors (ERs) have been …

Abstract mRNA stability is the mechanism by which cells protect transcripts allowing their
expression to execute various functions that affect cell metabolism and fate. It is well …

Coprinopsis cinerea is one of the model species used in fungal developmental studies. This
mushroom-forming Basidiomycetes fungus has several developmental destinies in …