[HTML][HTML] Emerging applications of nanotechnology in healthcare systems: Grand challenges and perspectives

S Anjum, S Ishaque, H Fatima, W Farooq, C Hano… - Pharmaceuticals, 2021 - mdpi.com
Healthcare, as a basic human right, has often become the focus of the development of
innovative technologies. Technological progress has significantly contributed to the …

Turmeric (Curcuma longa) and its major constituent (curcumin) as nontoxic and safe substances

V Soleimani, A Sahebkar… - Phytotherapy …, 2018 - Wiley Online Library
Curcumin is the major constituent of turmeric (Curcuma longa). Turmeric has been widely
used as a spice in foods and for therapeutic applications such as anti‐inflammatory …

Curcumin, the golden nutraceutical: multitargeting for multiple chronic diseases

AB Kunnumakkara, D Bordoloi… - British journal of …, 2017 - Wiley Online Library
Curcumin, a yellow pigment in the Indian spice Turmeric (Curcuma longa), which is
chemically known as diferuloylmethane, was first isolated exactly two centuries ago in 1815 …

Pharmaceutical strategies of improving oral systemic bioavailability of curcumin for clinical application

Z Ma, N Wang, H He, X Tang - Journal of Controlled Release, 2019 - Elsevier
Curcumin (Cur), a natural compound from Curcuma longa Linn, has various of
pharmacological activities such as anti-cancer, anti-inflammatory, anti-oxidant, anti …

Carotenoids: biochemistry, pharmacology and treatment

A Milani, M Basirnejad, S Shahbazi… - British journal of …, 2017 - Wiley Online Library
Carotenoids and retinoids have several similar biological activities such as antioxidant
properties, the inhibition of malignant tumour growth and the induction of apoptosis …

Nrf2–ARE pathway: an emerging target against oxidative stress and neuroinflammation in neurodegenerative diseases

I Buendia, P Michalska, E Navarro, I Gameiro… - Pharmacology & …, 2016 - Elsevier
Neurodegenerative diseases (NDDs) are predicted to be the biggest health concern in this
century and the second leading cause of death by 2050. The main risk factor of these …

Protective effects of Indian spice curcumin against amyloid-β in Alzheimer's disease

PH Reddy, M Manczak, X Yin… - Journal of …, 2018 - content.iospress.com
The purpose of our article is to assess the current understanding of Indian spice, curcumin,
against amyloid-ß (Aß)-induced toxicity in Alzheimer's disease (AD) pathogenesis. Natural …

Therapeutic roles of curcumin: lessons learned from clinical trials

SC Gupta, S Patchva, BB Aggarwal - The AAPS journal, 2013 - Springer
Extensive research over the past half century has shown that curcumin (diferuloylmethane),
a component of the golden spice turmeric (Curcuma longa), can modulate multiple cell …

[HTML][HTML] Review of the current state of protein aggregation inhibition from a materials chemistry perspective: Special focus on polymeric materials

R Rajan, S Ahmed, N Sharma, N Kumar, A Debas… - Materials …, 2021 - pubs.rsc.org
Protein instability caused by exposure to external additives or severe stress may result in
different diseases. Of these diseases, many are triggered by protein misfolding and …

Is curcumin bioavailability a problem in humans: Lessons from clinical trials

AB Kunnumakkara, C Harsha, K Banik… - Expert opinion on …, 2019 - Taylor & Francis
Introduction: Since ancient times, turmeric has been used in several folklore remedies
against various ailments. The principal component of turmeric is curcumin and its efficacy …