[HTML][HTML] Immune mechanisms linking obesity and preeclampsia

FT Spradley, AC Palei, JP Granger - Biomolecules, 2015 - mdpi.com
Preeclampsia (PE) is characterized by hypertension occurring after the twentieth week of
pregnancy. It is a significant contributor to maternal and perinatal morbidity and mortality in …

[HTML][HTML] COVID‐19—Associated dyslipidemia: Implications for mechanism of impaired resolution and novel therapeutic approaches

AV Sorokin, SK Karathanasis, ZH Yang… - The FASEB …, 2020 - ncbi.nlm.nih.gov
The current coronavirus disease 2019 (COVID‐19) pandemic presents a global challenge
for managing acutely ill patients and complications from viral infection. Systemic …

Hyperlipidaemia and cardioprotection: Animal models for translational studies

I Andreadou, R Schulz, L Badimon… - British journal of …, 2020 - Wiley Online Library
Hyperlipidaemia is a well‐established risk factor for cardiovascular diseases and therefore,
many animal model have been developed to mimic the human abnormal elevation of blood …

[HTML][HTML] Shear stress induces monocyte/macrophage-mediated inflammation by upregulating cell-surface expression of heat shock proteins

H Son, HS Choi, SE Baek, YH Kim, J Hur… - Biomedicine & …, 2023 - Elsevier
The loss of endothelial cells is associated with the accumulation of monocytes/macrophages
underneath the surface of the arteries, where cells are prone to mechanical stimulation, such …

The GLP-1 receptor agonist liraglutide inhibits progression of vascular disease via effects on atherogenesis, plaque stability and endothelial function in an ApoE−/− …

T Gaspari, I Welungoda, RE Widdop… - Diabetes and …, 2013 - journals.sagepub.com
Liraglutide, a once-daily glucagon-like peptide-1 receptor (GLP-1R) agonist, has been
approved as a new treatment for type 2 diabetes and is the subject of a clinical trial …

Atrasentan reduces albuminuria by restoring the glomerular endothelial glycocalyx barrier in diabetic nephropathy

MGS Boels, MC Avramut, A Koudijs, MJC Dane… - Diabetes, 2016 - Am Diabetes Assoc
Atrasentan, a selective endothelin A receptor antagonist, has been shown to reduce
albuminuria in type 2 diabetes. We previously showed that the structural integrity of a …

[HTML][HTML] Chronic administration of the probiotic kefir improves the endothelial function in spontaneously hypertensive rats

AGF Friques, CM Arpini, IC Kalil, AL Gava… - Journal of Translational …, 2015 - Springer
Background The beverage obtained by fermentation of milk with kefir grains, a complex
matrix containing acid bacteria and yeasts, has been shown to have beneficial effects in …

[HTML][HTML] Chronic iron overload intensifies atherosclerosis in apolipoprotein E deficient mice: Role of oxidative stress and endothelial dysfunction

VB Marques, MAS Leal, JGA Mageski, HG Fidelis… - Life sciences, 2019 - Elsevier
Aims We previously demonstrated that iron overload induces endothelial dysfunction and
oxidative stress, which could increase the risk for atherosclerosis. However, the iron-related …

[HTML][HTML] Soluble RAGE attenuates AngII-induced endothelial hyperpermeability by disrupting HMGB1-mediated crosstalk between AT1R and RAGE

J Jeong, J Lee, J Lim, S Cho, S An, M Lee… - … & Molecular Medicine, 2019 - nature.com
Increased endothelial permeability, one of the earliest signs of endothelial dysfunction, is
associated with the development of cardiovascular diseases such as hypertension and …

Chronic Cadmium Exposure Accelerates the Development of Atherosclerosis and Induces Vascular Dysfunction in the Aorta of ApoE−/− Mice

TF Oliveira, PR Batista, MA Leal… - Biological trace element …, 2019 - Springer
Cadmium exposure is related to cardiovascular diseases, including hypertension,
atherosclerosis, increased oxidative stress, endothelial dysfunction, and specific …