FYN: emerging biological roles and potential therapeutic targets in cancer
SF Peng, Y Fu - Journal of Translational Medicine, 2023 - Springer
Src family protein kinases (SFKs) play a key role in cell adhesion, invasion, proliferation,
survival, apoptosis, and angiogenesis during tumor development. In humans, SFKs consists …
survival, apoptosis, and angiogenesis during tumor development. In humans, SFKs consists …
Targeting inhibition of prognosis-related lipid metabolism genes including CYP19A1 enhances immunotherapeutic response in colon cancer
L Liu, M Mo, X Chen, D Chao, Y Zhang, X Chen… - Journal of Experimental …, 2023 - Springer
Background Lipid metabolic reprogramming in colon cancer shows a potential impact on
tumor immune microenvironment and is associated with response to immunotherapy …
tumor immune microenvironment and is associated with response to immunotherapy …
A novel cancer stemness‐related signature for predicting prognosis in patients with colon adenocarcinoma
W Wang, C Xu, Y Ren, S Wang, C Liao… - Stem cells …, 2021 - Wiley Online Library
Objective. To explore the cancer stemness features and develop a novel cancer stemness‐
related prognostic signature for colon adenocarcinoma (COAD). Methods. We downloaded …
related prognostic signature for colon adenocarcinoma (COAD). Methods. We downloaded …
Establishment of a prognostic risk prediction model incorporating disulfidptosis-related lncRNA for patients with prostate cancer
Y Mulati, C Lai, J Luo, J Hu, X Xu, D Kong, Y Xiao… - BMC cancer, 2024 - Springer
Abstract Purpose Prostate cancer (PCa) is one of the major tumor diseases that threaten
men's health globally, and biochemical recurrence significantly impacts its prognosis …
men's health globally, and biochemical recurrence significantly impacts its prognosis …
Effects of lipid metabolism‐related genes PTGIS and HRASLS on phenotype, prognosis, and tumor immunity in lung squamous cell carcinoma
K Lei, R Liang, B Tan, L Li, Y Lyu… - Oxidative Medicine …, 2023 - Wiley Online Library
Background. Lipid metabolism reprogramming played an important role in cancer
occurrence, development, and immune regulation. The aim of this study was to identify and …
occurrence, development, and immune regulation. The aim of this study was to identify and …
Comprehensive characterization of RNA-binding proteins in colon adenocarcinoma identifies a novel prognostic signature for predicting clinical outcomes and …
Y Miao, Q Yuan, C Wang, X Feng… - … Chemistry & High …, 2023 - ingentaconnect.com
Background: RNA-binding proteins (RBPs) are crucial factors that function in the
posttranscriptional modification process and are significant in cancer. Objective: This …
posttranscriptional modification process and are significant in cancer. Objective: This …
Identification of potential molecular mechanism related to infertile endometriosis
X Li, L Guo, W Zhang, J He, L Ai, C Yu… - Frontiers in veterinary …, 2022 - frontiersin.org
Objectives In this research, we aim to explore the bioinformatic mechanism of infertile
endometriosis in order to identify new treatment targets and molecular mechanism. Methods …
endometriosis in order to identify new treatment targets and molecular mechanism. Methods …
A novel lipid metabolism-based risk model associated with immunosuppressive mechanisms in diffuse large B-cell lymphoma
Z Zhang, C Zhao, S Yang, W Lu, J Shi - Lipids in Health and Disease, 2024 - Springer
Background The molecular diversity exhibited by diffuse large B-cell lymphoma (DLBCL) is
a significant obstacle facing current precision therapies. However, scoring using the …
a significant obstacle facing current precision therapies. However, scoring using the …
Construction and experimental validation of a macrophage cell senescence-related gene signature to evaluate the prognosis, immunotherapeutic sensitivity, and …
Q Jiang, J Zhou, Q Chen, Y Huang, C Yang… - Functional & Integrative …, 2023 - Springer
Tumor-associated macrophages (TAMs) are pivotal components of tumor microenvironment
(TME), and senescent TAMs contribute to the alternation of the profiles of TME. However, the …
(TME), and senescent TAMs contribute to the alternation of the profiles of TME. However, the …
Metabolic reprogramming, autophagy, and ferroptosis: Novel arsenals to overcome immunotherapy resistance in gastrointestinal cancer
X Wang, L Zhou, H Wang, W Chen, L Jiang… - Cancer …, 2023 - Wiley Online Library
Background Gastrointestinal cancer poses a serious health threat owing to its high morbidity
and mortality. Although immune checkpoint blockade (ICB) therapies have achieved …
and mortality. Although immune checkpoint blockade (ICB) therapies have achieved …