Background: Acute kidney injury (AKI) is associated with damage to the nephrons and
tubular epithelial cells (TECs), which can lead to chronic kidney disease and end-stage …

Diabetic kidney disease, known as a glomerular disease, arises from a metabolic disorder
impairing renal cell function. Mitochondria, crucial organelles, play a key role in substance …

Excessive production of renal reactive oxygen species (ROS) plays a major role in diabetic
kidney disease (DKD). Here, we provide key findings demonstrating the predominant …

Background: Acute kidney injury (AKI) is a common syndrome impacting about 13.3 million
patients per year. Tilianin has been reported to alleviate myocardial ischemia/reperfusion …

Abstract Ethnopharmacological relevance Fructus Ligustri Lucidi (FLL), the fruit of Ligustrum
lucidum Ait., is a traditional Chinese medicine that has been used for tonifying the kidney …

Frugivory evolved multiple times in mammals, including bats. However, the cellular and
molecular components driving it remain largely unknown. Here, we use integrative single …

Aims The increasing incidence of chronic kidney disease (CKD) urgently calls for effective
nephroprotective agents. Traditional Chinese Medicine Angelica sinensis and its formula …

Chronic hyperglycemia induces intrarenal oxidative stress due to the excessive production
of reactive oxygen species (ROS), leading to a cascade of events that contribute to the …

Renal ischemia–reperfusion (IR) causes acute kidney injury due to oxidative stress, tubular
inflammation, and apoptosis. Early growth response 1 (Egr-1) is a transcription factor …

Abstract Glycogen Storage Disease Type I (GSDI) is an inherited disease caused by glucose-
6 phosphatase (G6Pase) deficiency, leading to a loss of endogenous glucose production …