Background The aim of this study was to develop a method to study genome-wide local
translation in biochemically isolated synaptic fractions (synaptoneurosomes). This …

The predominant 18.5-kDa classic myelin basic protein (MBP) is mainly responsible for
compaction of the myelin sheath in the central nervous system, but is multifunctional, having …

The intrinsically disordered 18.5 kDa classic isoform of MBP (myelin basic protein) interacts
with Fyn kinase during oligodendrocyte development and myelination. It does so primarily …

Myelin sheaths surrounding axons are essential for saltatory conduction of nerve impulse in
the central nervous system. A major protein constituent of myelin sheaths is produced by the …

Abstract SVIP (small p97/VCP-interacting protein) was initially identified as one of many
cofactors regulating the valosin containing protein (VCP), an AAA+ ATPase involved in …

The shortest sequence of amino acids in protein containing functional and structural
information is a “motif.” To understand myelin protein functions, we intensively searched for …

Astrocytes being the most abundant cell types in the mammalian brain are intimately
associated with a plethora of functions that are vital to central nervous system (CNS) …

We have parameterized and evaluated the proline homologue Aze (azetidine-2-carboxylic
acid) for the gromos56a3 force-field for use in molecular dynamics simulations using …

Purpose During a neuronal injury, a variety of immune cells infiltrate into the local
microenvironment at the demyelination site. After the destruction of the intact myelin sheath …

The putative membrane protein U24 from HHV-6A shares a seven-residue sequence
identity (which includes a PxxP motif) with myelin basic protein (MBP), a protein responsible …