Depression is a heterogeneous and etiologically complex psychiatric syndrome, not a
unitary disease entity, encompassing a broad spectrum of psychopathology arising from …

The fundamental importance of prefrontal cortical connectivity to information processing and,
therefore, disorders of cognition, emotion, and behavior has been recognized for decades …

The mechanisms underlying phenotypic heterogeneity in autism spectrum disorder (ASD)
are not well understood. Using a large neuroimaging dataset, we identified three latent …

Gene expression fundamentally shapes the structural and functional architecture of the
human brain. Open-access transcriptomic datasets like the Allen Human Brain Atlas provide …

Major depressive disorder (MDD) has been shown to be associated with structural
abnormalities in a variety of spatially diverse brain regions. However, the correlation …

Studies of large-scale brain organization have revealed interesting relationships between
spatial gradients in brain maps across multiple modalities. Evaluating the significance of …

The brain is a complex system comprising a myriad of interacting neurons, posing significant
challenges in understanding its structure, function, and dynamics. Network science has …

Numerous brain disorders demonstrate structural brain abnormalities, which are thought to
arise from molecular perturbations or connectome miswiring. The unique and shared …

Neurodevelopmental disorders have a heritable component and are associated with region
specific alterations in brain anatomy. However, it is unclear how genetic risks for …

Major depressive disorder emerges from the complex interactions of biological systems that
span genes and molecules through cells, networks, and behavior. Establishing how …