Pathophysiology of the right ventricle in health and disease: an update

K Tello, R Naeije, F de Man… - Cardiovascular research, 2023 - academic.oup.com
The contribution of the right ventricle (RV) to cardiac output is negligible in normal resting
conditions when pressures in the pulmonary circulation are low. However, the RV becomes …

Stem cell therapy in pulmonary hypertension: current practice and future opportunities

R Zheng, T Xu, X Wang, L Yang… - European Respiratory …, 2023 - Eur Respiratory Soc
Pulmonary hypertension (PH) is a progressive disease characterised by elevated pulmonary
arterial pressure and right-sided heart failure. While conventional drug therapies, including …

Comparative effectiveness of sotatercept and approved add-on pulmonary arterial hypertension therapies: a systematic review and network meta-analysis

T Pitre, K Desai, J Mah, D Zeraatkar… - Annals of the American …, 2024 - atsjournals.org
Rationale: There are no direct comparisons of sotatercept to add-on therapies approved for
PAH. Objective: This study aimed to compare the efficacy and safety of add-on sotatercept …

Prognostic role of haemodynamics at follow-up in patients with pulmonary arterial hypertension: a challenge to current ESC/ERS risk tools

F Dardi, D Guarino, A Ballerini, R Bertozzi… - ERJ Open …, 2024 - Eur Respiratory Soc
Background Hemodynamic variables like right atrial pressure (RAP), cardiac index (CI),
stroke volume index (SVI) and mixed venous oxygen saturation (SvO2) predict survival in …