Blessings in disguise: Bio-functional benefits of grape seed extracts

JA Nowshehri, ZA Bhat, MY Shah - Food Research International, 2015 - Elsevier
Grapes (Vitis vinifera) are one of the largest fruit crops in the world, with an annual
production of 69 million metric tons. They are a good source of polyphenolic compounds …

Cubosomes as a potential oral drug delivery system for enhancing the hepatoprotective effect of coenzyme Q10

AM Mohsen, MM Younis, A Salama… - Journal of Pharmaceutical …, 2021 - Elsevier
Abstract Coenzyme Q10 (CoQ10) acts as an antioxidant that protects the cells by preventing
lipid peroxidation. Owing to its low solubility, CoQ10 has shown poor delivery properties and …

Chrysin attenuates liver fibrosis and hepatic stellate cell activation through TGF-β/Smad signaling pathway

C Balta, H Herman, OM Boldura, I Gasca… - Chemico-biological …, 2015 - Elsevier
We investigated the protective effect of chrysin on chronic liver fibrosis in mice and the
potential mechanism underlying TGF-β1-mediated hepatic stellate cells (HSCs) activation …

The protective effects of silymarin on thioacetamide-induced liver damage: measurement of miR-122, miR-192, and miR-194 levels

O Teksoy, V Sahinturk, M Cengiz, B İnal… - Applied biochemistry and …, 2020 - Springer
This study aims to investigate the protective effects of silymarin (Sm) in thioacetamide (TAA)-
related liver damage. What makes this study special is that it attempts to determine the …

Anti-inflammatory, antiapoptotic and proproliferative effects of vitis vinifera seed ethanolic extract in the liver of streptozotocin-nicotinamide-induced type 2 diabetes in …

N Giribabu, K Karim, EK Kilari, NM Kassim… - Canadian journal of …, 2018 - Elsevier
Abstract Objectives Consumption of Vitis vinifera seed has been reported to ameliorate liver
pathology in diabetes mellitus; however, the mechanisms underlying its effects remain …

[HTML][HTML] Mast cells and pro-inflammatory cytokines roles in assessment of grape seeds extract anti-inflammatory activity in rat model of carrageenan-induced paw …

AAM Abd-Allah, NAMN El-Deen… - Iranian journal of …, 2018 - ncbi.nlm.nih.gov
Objective (s): Reactive oxygen species (ROS)-produced oxidative disorders were involved
at the pathophysiology of many inflammatory processes via the generation of pro …

[HTML][HTML] In vivo anticancer effects of Momordica charantia seed fat on hepatocellular carcinoma in a rat model

KNK Ranasinghe, AD Premarathna… - Journal of Ayurveda and …, 2021 - Elsevier
Background Momordica charantia or bitter melon is a well-known vegetable with a number
of therapeutic actions in Ayurvedic medicine. Alpha-eleostearic acid, a conjugated trienoic …

Histological and immunohistochemical study of cardiac telocytes in a rat model of isoproterenol-induced myocardial infarction with a reference to the effect of grape …

MS Nour, NR Sarhan, SA Mazroa, SA Gawish - Acta histochemica, 2017 - Elsevier
Abstract Introduction Cardiac telocytes (TCs) represent a unique type of cells that make a
supportive network for stem cells that contribute in cardiac renewal, but their role during …

Grape seed extract improved the fertility-enhancing effect of atorvastatin in high-fat diet-induced testicular injury in rats: involvement of antioxidant and anti-apoptotic …

DK Abdulwahab, WW Ibrahim… - Journal of Pharmacy …, 2021 - academic.oup.com
Objectives Reduced male fertility is highly prevalent with hypercholesterolaemia. Though
statins are drugs of choice for hypercholesterolaemia, their effect on male fertility is still …

Heat shock protein 47 as indispensible participant in liver fibrosis: possible protective effect of lactoferrin

FH Rizk, NI Sarhan, NA Soliman, MAA Ibrahim… - IUBMB …, 2018 - Wiley Online Library
Lactoferrin (LF) was previously suggested to have a protective effect against liver fibrosis by
preventing hepatic stellate cells (HSCs) activation. The effect of LF on heat shock protein 47 …