[HTML][HTML] Experimental and clinical treatment of Chagas disease: a review

PAS Junior, I Molina, SMF Murta… - The American journal …, 2017 - ncbi.nlm.nih.gov
Chagas disease (CD) is caused by the protozoan parasite Trypanosoma cruzi that infects a
broad range of triatomines and mammalian species, including man. It afflicts 8 million …

Diagnosis and management of Chagas disease and cardiomyopathy

AL Ribeiro, MP Nunes, MM Teixeira… - Nature Reviews …, 2012 - nature.com
Chagas cardiomyopathy is the most severe and life-threatening manifestation of human
Chagas disease—a'neglected'tropical disease caused by the protozoan parasite …

[PDF][PDF] The potential of secondary metabolites from plants as drugs or leads against protozoan neglected diseases-part II

TJ Schmidt, SA Khalid, AJ Romanha, TMA Alves… - 2012 - lavierebelle.org
Infections with protozoan parasites are a major cause of disease and mortality in many
tropical countries of the world. Diseases caused by species of the genera Trypanosoma …

In vitro and in vivo experimental models for drug screening and development for Chagas disease

AJ Romanha, SL Castro, MNC Soeiro… - Memórias do Instituto …, 2010 - SciELO Brasil
Chagas disease, a neglected illness, affects nearly 12-14 million people in endemic areas of
Latin America. Although the occurrence of acute cases sharply has declined due to …

[HTML][HTML] Neglected infections of poverty in the United States of America

PJ Hotez - PLoS neglected tropical diseases, 2008 - journals.plos.org
In the United States, there is a largely hidden burden of diseases caused by a group of
chronic and debilitating parasitic, bacterial, and congenital infections known as the …

Immunoregulatory networks in human C hagas disease

WO Dutra, CAS Menezes, LMD Magalhães… - Parasite …, 2014 - Wiley Online Library
Chagas disease, caused by the infection with T rypanosoma cruzi, is endemic in all L atin A
merica. Due to the increase in population migration, C hagas disease has spread worldwide …

[HTML][HTML] The trypanocidal activity of naphthoquinones: a review

AV Pinto, SL de Castro - Molecules, 2009 - ncbi.nlm.nih.gov
Naphthoquinones are compounds present in several families of higher plants. Their
molecular structures confer redox properties, and they are involved in multiple biological …

Chagas cardiomyopathy—where do we stand after a hundred years?

A Biolo, AL Ribeiro, N Clausell - Progress in cardiovascular diseases, 2010 - Elsevier
A hundred years from its description, Chagas cardiomyopathy remains a challenging
disease. Although successful vector-control strategies have decreased the incidence of …

Plasma cytokine expression is associated with cardiac morbidity in chagas disease

GR Sousa, JAS Gomes, RCG Fares, MPS Damásio… - PloS one, 2014 - journals.plos.org
The expression of immune response appears to be associated with morbidity in Chagas
disease. However, the studies in this field have usually employed small samples of patients …

Novel amidines and analogues as promising agents against intracellular parasites: a systematic review

MNC Soeiro, K Werbovetz, DW Boykin, WD Wilson… - Parasitology, 2013 - cambridge.org
Parasitic protozoa comprise diverse aetiological agents responsible for important diseases
in humans and animals including sleeping sickness, Chagas disease, leishmaniasis …