In the last two decades, extracellular vesicle-mediated communication between cells has
become a major field in cell biology. However, the function of extracellular vesicles is far …

Intracellular membrane traffic defines a complex network of pathways that connects many of
the membrane-bound organelles of eukaryotic cells. Although each pathway is governed by …

Lysosome‐related organelles (LROs) comprise a diverse group of cell type‐specific,
membrane‐bound subcellular organelles that derive at least in part from the endolysosomal …

The cytoskeleton is an interconnected network that provides support and organization to
cells. In eukaryotes, its main components include actin and microtubules, two types of …

Albinism is a rare genetic condition globally characterized by a number of specific deficits in
the visual system, resulting in poor vision, in association with a variable hypopigmentation …

Rab27, a member of the small GTPase Rab family, is widely conserved in metazoan, and
two Rab27 isoforms, Rab27A and Rab27B, are present in vertebrates. Rab27A was the first …

Rab molecular switches are key players in defining membrane identity and regulating
intracellular trafficking events in eukaryotic cells. In spite of their global structural similarity …

Melanogenesis is the unique process of producing pigmented biopolymers that are
sequestered within melanosomes, which provides color to the skin, hair and eyes of animals …

As the prototype of unconventional myosin motor family, myosin Va (MyoVa) transport
cellular cargos along actin filaments in diverse cellular processes. The off-duty MyoVa …

Simple Summary Melanoma is produced by the malignant transformation of the pigmented
cells in the skin. It is the deadliest form of skin cancer and a global medical burden. Recent …