Lung cancer is among the most prevalent and leading causes of death worldwide. The
major reason for high mortality is the late diagnosis of the disease, and in most cases, lung …

Cancer stemness is associated with high malignancy and low differentiation, as well as
therapeutic resistance of tumors including pancreatic ductal adenocarcinoma (PDAC) …

Fibroblast growth factor receptor (FGFR) includes four highly conserved transmembrane
receptor tyrosine kinases (FGFR1-4). FGF and FGFR regulate many biological processes …

Gastrointestinal stromal tumors (GIST) are rare neoplasms of mesenchymal origin arising in
the gastrointestinal tract. The vast majority are characterized by mutually exclusive activating …

Simple Summary Cholangiocarcinoma (CCA) is a cancer arising from the bile ducts.
Chemotherapy has long been the standard of care for metastatic CCA, but recent clinical …

Gastric cancer (GC) is one of the most wide-spread malignancies in the world. The
oncogenic role of signaling of fibroblast growing factors (FGFs) and their receptors (FGFRs) …

Rogaratinib (BAY 1163877) is a highly potent and selective small‐molecule pan‐fibroblast
growth factor receptor (FGFR) inhibitor (FGFR1–4) for oral application currently being …

Neural cell adhesion molecule, an integrated molecule of immunoglobulin protein
superfamily involved in cell-cell adhesion, undergoes various structural modifications …

Cancer is becoming more common worldwide, impacting the vast majority of people. As a
result, new anticancer drugs are currently being created, and their safety is still being …

Simple Summary Pancreatic ductal adenocarcinoma (PDAC) is a deadly malignancy that is
projected to become the leading cause of cancer death by 2050. Fibroblast growth factor …