Abstract Background & Aims Recently, overexpression of the fibroblast growth factor
receptor 3 (FGFR3) splice variants FGFR3‐IIIb and FGFR3‐IIIc was found in~ 50% of …

The binding of fibroblast growth factor (FGF) ligands to their respective receptors (FGFR) at
the cell surface results in activation of downstream intracellular signalling pathways …

Intrahepatic cholangiocarcinoma (iCCA) is an anatomically and biologically distinct entity
with a rising incidence and a poor prognosis on conventional treatments. Surgery followed …

Background The gene encoding fibroblast growth factor receptor 1 (FGFR1) is emerging as
a therapeutic and prognostic biomarker in various cancer types, including head and neck …

Aberrant activation of the fibroblast growth factor 19-fibroblast growth factor receptor 4
(FGF19-FGFR4) signaling pathway has been proved to promote hepatocellular carcinoma …

Fibroblast growth factor receptor 1 (FGFR1) is an integral membrane protein that transmits
prolife signals through the plasma membrane. Overexpression of FGFR1 has been reported …

The worldwide prevalence of lung cancer is amongst the greatest of all cancers, and deaths
due to lung cancer are the highest. Current researches are focusing on a molecular …

Ovarian cancer, cervical cancer and endometrial cancer are three relatively common
malignant cancers of the female reproductive system. Despite improvements in female …

Fibroblast growth factors (FGFs) and their plasma membrane-localized receptors (FGFRs)
play a key role in the regulation of developmental processes and metabolism. Aberrant …

Fibroblast growth factors (FGFs) act as proangiogenic and mitogenic cytokines in several
cancers, including multiple myeloma (MM). Indeed, corrupted FGF autocrine and paracrine …