Apoptotic cell death in disease—Current understanding of the NCCD 2023
I Vitale, F Pietrocola, E Guilbaud… - Cell Death & …, 2023 - nature.com
Apoptosis is a form of regulated cell death (RCD) that involves proteases of the caspase
family. Pharmacological and genetic strategies that experimentally inhibit or delay apoptosis …
family. Pharmacological and genetic strategies that experimentally inhibit or delay apoptosis …
Immune and inflammatory mechanisms of abdominal aortic aneurysm
AC Marquez-Sanchez, EK Koltsova - Frontiers in immunology, 2022 - frontiersin.org
Abdominal aortic aneurysm (AAA) is a life-threatening cardiovascular disease. Immune-
mediated infiltration and a destruction of the aortic wall during AAA development plays …
mediated infiltration and a destruction of the aortic wall during AAA development plays …
From traditional pharmacological towards nucleic acid-based therapies for cardiovascular diseases
U Landmesser, W Poller, S Tsimikas… - European heart …, 2020 - academic.oup.com
Nucleic acid-based therapeutics are currently developed at large scale for prevention and
management of cardiovascular diseases (CVDs), since:(i) genetic studies have highlighted …
management of cardiovascular diseases (CVDs), since:(i) genetic studies have highlighted …
Mouse models for abdominal aortic aneurysm
Abdominal aortic aneurysm (AAA) rupture is estimated to cause 200,000 deaths each year.
Currently, the only treatment for AAA is surgical repair; however, this is only indicated for …
Currently, the only treatment for AAA is surgical repair; however, this is only indicated for …
Cyclodextrin prevents abdominal aortic aneurysm via activation of vascular smooth muscle cell transcription factor EB
Background: Abdominal aortic aneurysm (AAA) is a severe aortic disease with a high
mortality rate in the event of rupture. Pharmacological therapy is needed to inhibit AAA …
mortality rate in the event of rupture. Pharmacological therapy is needed to inhibit AAA …
Programmed cell death in aortic aneurysm and dissection: a potential therapeutic target
Rupture of aortic aneurysm and dissection (AAD) remains a leading cause of death.
Progressive smooth muscle cell (SMC) loss is a crucial feature of AAD that contributes to …
Progressive smooth muscle cell (SMC) loss is a crucial feature of AAD that contributes to …
Akkermansia muciniphila Alters Gut Microbiota and Immune System to Improve Cardiovascular Diseases in Murine Model
X He, Y Bai, H Zhou, K Wu - Frontiers in microbiology, 2022 - frontiersin.org
The gut microbiota plays an important role in a variety of cardiovascular diseases. The
probiotics screened based on microbiota can effectively improve metabolism and immune …
probiotics screened based on microbiota can effectively improve metabolism and immune …
Importance of NLRP3 inflammasome in abdominal aortic aneurysms
Abdominal aortic aneurysm (AAA) is a chronic inflammatory degenerative aortic disease,
which particularly affects older people. Nucleotide-binding oligomerization domain-like …
which particularly affects older people. Nucleotide-binding oligomerization domain-like …
The role of RIPK1 and RIPK3 in cardiovascular disease
E DeRoo, T Zhou, B Liu - International Journal of Molecular Sciences, 2020 - mdpi.com
Cardiovascular diseases, including peripheral arterial and venous disease, myocardial
infarction, and stroke, are the number one cause of death worldwide annually. In the last 20 …
infarction, and stroke, are the number one cause of death worldwide annually. In the last 20 …
H2S alleviates aortic aneurysm and dissection: Crosstalk between transforming growth factor 1 signaling and NLRP3 inflammasome
J Cui, G Xu, F Bian - International Journal of Cardiology, 2021 - Elsevier
Background Vascular remodeling and inflammation are involved in aortic aneurysm (AA)
and aortic dissection (AD). TGF-β1 signaling is involved in tissue fibrosis, extracellular matrix …
and aortic dissection (AD). TGF-β1 signaling is involved in tissue fibrosis, extracellular matrix …