Apoptosis is a form of regulated cell death (RCD) that involves proteases of the caspase
family. Pharmacological and genetic strategies that experimentally inhibit or delay apoptosis …

Abdominal aortic aneurysm (AAA) is a life-threatening cardiovascular disease. Immune-
mediated infiltration and a destruction of the aortic wall during AAA development plays …

Nucleic acid-based therapeutics are currently developed at large scale for prevention and
management of cardiovascular diseases (CVDs), since:(i) genetic studies have highlighted …

Abdominal aortic aneurysm (AAA) rupture is estimated to cause 200,000 deaths each year.
Currently, the only treatment for AAA is surgical repair; however, this is only indicated for …

Background: Abdominal aortic aneurysm (AAA) is a severe aortic disease with a high
mortality rate in the event of rupture. Pharmacological therapy is needed to inhibit AAA …

Rupture of aortic aneurysm and dissection (AAD) remains a leading cause of death.
Progressive smooth muscle cell (SMC) loss is a crucial feature of AAD that contributes to …

The gut microbiota plays an important role in a variety of cardiovascular diseases. The
probiotics screened based on microbiota can effectively improve metabolism and immune …

Abdominal aortic aneurysm (AAA) is a chronic inflammatory degenerative aortic disease,
which particularly affects older people. Nucleotide-binding oligomerization domain-like …

Cardiovascular diseases, including peripheral arterial and venous disease, myocardial
infarction, and stroke, are the number one cause of death worldwide annually. In the last 20 …

Background Vascular remodeling and inflammation are involved in aortic aneurysm (AA)
and aortic dissection (AD). TGF-β1 signaling is involved in tissue fibrosis, extracellular matrix …