Hypertrophic scars and keloids can have significant detrimental effects on patients both
psychosocially and functionally. A careful identification of patient risk factors and a …

Significance: With an aging population leading to an increase in diabetes and associated
cutaneous wounds, there is a pressing clinical need to improve wound-healing therapies …

Chronic non-healing wounds represent one of the most common complications of diabetes
and need advanced treatment strategies. Exosomes are key mediators of cell paracrine …

Chronic skin wounds represent one of the most common and disabling complications of
diabetes. Endothelial progenitor cells (EPCs) are precursors of endothelial cells and can …

Background/Aims: Diabetic non-healing skin ulcers represent a serious challenge in clinical
practice, in which the hyperglycemia-induced disturbance of angiogenesis, and endothelial …

Background Distraction osteogenesis (DO) is an effective but lengthy procedure to fully
induce bone regeneration in large bone defects. Accumulating evidence supports the role of …

Background Patients with diabetic cutaneous ulcers experience financial burden and a
lower quality of life and life expectancy. Endothelial progenitor cell (EPC)-derived exosomes …

Endothelial progenitor cells (EPCs) play an important role in repairing damaged blood
vessels and promoting neovascularization. However, the specific mechanism of EPCs …

Diabetes induces a decrease in the number and function of different pro-angiogenic cell
types generically designated as putative endothelial progenitor cells (EPC), which …

Optimum healing of a cutaneous wound involves a well‐orchestrated cascade of biological
and molecular processes involving cell migration, proliferation, extracellular matrix …