Cell-based and stem-cell-based treatments for spinal cord injury: evidence from clinical trials
Spinal cord injury is a severely disabling neurological condition leading to impaired mobility,
pain, and autonomic dysfunction. Most often, a single traumatic event, such as a traffic or …
pain, and autonomic dysfunction. Most often, a single traumatic event, such as a traffic or …
Peripheral white blood cell responses as emerging biomarkers for patient stratification and prognosis in acute spinal cord injury
Peripheral white blood cell responses as emerging biomarkers... : Current Opinion in
Neurology Peripheral white blood cell responses as emerging biomarkers for patient …
Neurology Peripheral white blood cell responses as emerging biomarkers for patient …
Pathophysiology, classification and comorbidities after traumatic spinal cord injury
J Guest, N Datta, G Jimsheleishvili… - Journal of personalized …, 2022 - mdpi.com
The spinal cord is a conduit within the central nervous system (CNS) that provides ongoing
communication between the brain and the rest of the body, conveying complex sensory and …
communication between the brain and the rest of the body, conveying complex sensory and …
Segmental motor recovery after cervical spinal cord injury relates to density and integrity of corticospinal tract projections
G Balbinot, G Li, S Kalsi-Ryan, R Abel, D Maier… - Nature …, 2023 - nature.com
Cervical spinal cord injury (SCI) causes extensive impairments for individuals which may
include dextrous hand function. Although prior work has focused on the recovery at the …
include dextrous hand function. Although prior work has focused on the recovery at the …
Association of CSF and serum neurofilament light and glial fibrillary acidic protein, injury severity, and outcome in spinal cord injury
Background and Objectives Traumatic spinal cord injury (SCI) is highly heterogeneous, and
tools to better delineate pathophysiology and recovery are needed. Our objective was to …
tools to better delineate pathophysiology and recovery are needed. Our objective was to …
International surveillance study in acute spinal cord injury confirms viability of multinational clinical trials
L Bourguignon, B Tong, F Geisler, M Schubert… - BMC medicine, 2022 - Springer
Background The epidemiological international landscape of traumatic spinal cord injury
(SCI) has evolved over the last decades along with given inherent differences in acute care …
(SCI) has evolved over the last decades along with given inherent differences in acute care …
Management of acute spinal cord injury: Where have we been? Where are we now? Where are we going?
The strides that have been achieved in the realm of spinal cord injury (SCI) management are
remarkable. It is likely that 90% of what has been recognized to date about SCI …
remarkable. It is likely that 90% of what has been recognized to date about SCI …
Spontaneous motor recovery after cervical spinal cord injury: issues for nerve transfer surgery decision making
J Dengler, JD Steeves, A Curt, M Mehra, CB Novak… - Spinal cord, 2022 - nature.com
Study design Retrospective cohort study. Objectives To quantify spontaneous upper
extremity motor recovery between 6 and 12 months after spinal cord injury (SCI) to help …
extremity motor recovery between 6 and 12 months after spinal cord injury (SCI) to help …
Impact of surgical timing on motor level lowering in motor complete traumatic spinal cord injury patients
PV Ter Wengel, EEA de Gendt, E Martin… - Journal of …, 2022 - liebertpub.com
Patients with complete traumatic spinal cord injury (tSCI) have a low potential to recover
ambulation. Motor level recovery, adjacent to the level of injury, could influence functional …
ambulation. Motor level recovery, adjacent to the level of injury, could influence functional …
Association of upper-limb neurological recovery with functional outcomes in high cervical spinal cord injury
OBJECTIVE High cervical spinal cord injury (SCI) results in complete loss of upper-limb
function, resulting in debilitating tetraplegia and permanent disability. Spontaneous motor …
function, resulting in debilitating tetraplegia and permanent disability. Spontaneous motor …