Gene therapy: Comprehensive overview and therapeutic applications

N Sayed, P Allawadhi, A Khurana, V Singh, U Navik… - Life sciences, 2022 - Elsevier
Gene therapy is the product of man's quest to eliminate diseases. Gene therapy has three
facets namely, gene silencing using siRNA, shRNA and miRNA, gene replacement where …

[HTML][HTML] Magnetite nanoparticles in magnetic hyperthermia and cancer therapies: Challenges and perspectives

A Włodarczyk, S Gorgoń, A Radoń, K Bajdak-Rusinek - Nanomaterials, 2022 - mdpi.com
Until now, strategies used to treat cancer are imperfect, and this generates the need to
search for better and safer solutions. The biggest issue is the lack of selective interaction …

[HTML][HTML] Stimuli-responsive materials for tissue engineering and drug delivery

S Municoy, MI Alvarez Echazu, PE Antezana… - International Journal of …, 2020 - mdpi.com
Smart or stimuli-responsive materials are an emerging class of materials used for tissue
engineering and drug delivery. A variety of stimuli (including temperature, pH, redox-state …

Recent advances in the development of gene delivery systems

YK Sung, SW Kim - Biomaterials research, 2019 - spj.science.org
Background Gene delivery systems are essentially necessary for the gene therapy of human
genetic diseases. Gene therapy is the unique way that is able to use the adjustable gene to …

Hyaluronic acid-functionalized lipoplexes and polyplexes as emerging nanocarriers for receptor-targeted cancer therapy

J Chandra, N Molugulu, S Annadurai, S Wahab… - Environmental …, 2023 - Elsevier
Cancer is an intricate disease that develops as a response to a combination of hereditary
and environmental risk factors, which then result in a variety of changes to the genome. The …

[HTML][HTML] Therapeutic applications of nanobiotechnology

Y Dutt, RP Pandey, M Dutt, A Gupta, A Vibhuti… - Journal of …, 2023 - Springer
Nanobiotechnology, as a novel and more specialized branch of science, has provided a
number of nanostructures such as nanoparticles, by utilizing the methods, techniques, and …

[HTML][HTML] Nanoparticle drug delivery systems for synergistic delivery of tumor therapy

D Chen, X Liu, X Lu, J Tian - Frontiers in Pharmacology, 2023 - frontiersin.org
Nanoparticle drug delivery systems have proved anti-tumor effects; however, they are not
widely used in tumor therapy due to insufficient ability to target specific sites, multidrug …

Encapsulation, visualization and expression of genes with biomimetically mineralized zeolitic imidazolate framework‐8 (ZIF‐8)

A Poddar, JJ Conesa, K Liang, S Dhakal, P Reineck… - Small, 2019 - Wiley Online Library
Recent work in biomolecule‐metal–organic framework (MOF) composites has proven to be
an effective strategy for the protection of proteins. However, for other biomacromolecules …

[HTML][HTML] Targeted liposomes: A nonviral gene delivery system for cancer therapy

MT Luiz, JAP Dutra, LB Tofani, JTC de Araújo… - Pharmaceutics, 2022 - mdpi.com
Cancer is the second most frequent cause of death worldwide, with 28.4 million new cases
expected for 2040. Despite de advances in the treatment, it remains a challenge because of …

Pathophysiological aspects and therapeutic armamentarium of Alzheimer's disease: recent trends and future development

BP Dave, YB Shah, KG Maheshwari… - Cellular and Molecular …, 2023 - Springer
Alzheimer's disease (AD) is the primary cause of dementia and is characterized by the death
of brain cells due to the accumulation of insoluble amyloid plaques, hyperphosphorylation of …