IL-17 and IL-17-producing cells in protection versus pathology

KHG Mills - Nature Reviews Immunology, 2023 - nature.com
IL-17 cytokine family members have diverse biological functions, promoting protective
immunity against many pathogens but also driving inflammatory pathology during infection …

COVID-19 infection: an overview on cytokine storm and related interventions

S Montazersaheb, SM Hosseiniyan Khatibi, MS Hejazi… - Virology journal, 2022 - Springer
Abstract Coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory
syndrome coronavirus-2 (SARS-CoV-2) has posed a significant threat to global health. This …

Obesity as a risk factor for severe COVID-19 and complications: a review

F Demeulemeester, K de Punder, M van Heijningen… - Cells, 2021 - mdpi.com
Emerging data suggest that obesity is a major risk factor for the progression of major
complications such as acute respiratory distress syndrome (ARDS), cytokine storm and …

Prospective roles of tumor necrosis factor-alpha (TNF-α) in COVID-19: prognosis, therapeutic and management

Z Mohd Zawawi, J Kalyanasundram… - International journal of …, 2023 - mdpi.com
The coronavirus disease 2019 (COVID-19) became a worldwide concern at the beginning of
2020 and has affected millions. Several previous studies revealed the impact of the …

Quercetin as a potential treatment for COVID-19-induced acute kidney injury: Based on network pharmacology and molecular docking study

YY Gu, M Zhang, H Cen, YF Wu, Z Lu, F Lu, XS Liu… - PloS one, 2021 - journals.plos.org
Kidneys are one of the targets for SARS-CoV-2, it is reported that up to 36% of patients with
SARS-CoV-2 infection would develop into acute kidney injury (AKI). AKI is associated with …

High levels of immunosuppression are related to unfavourable outcomes in hospitalised patients with rheumatic diseases and COVID-19: first results of ReumaCoV …

CDL Marques, AM Kakehasi, MM Pinheiro… - RMD open, 2021 - rmdopen.bmj.com
Objectives To evaluate risk factors associated with unfavourable outcomes: emergency care,
hospitalisation, admission to intensive care unit (ICU), mechanical ventilation and death in …

Natural dietary and medicinal plants with anti-obesity therapeutics activities for treatment and prevention of obesity during lock down and in post-COVID-19 era

W Sun, MH Shahrajabian, Q Cheng - Applied Sciences, 2021 - mdpi.com
Overweight and obesity have become global epidemics, especially during the lockdown due
to the COVID-19 pandemic. The potential of medicinal plants as a better and safe option in …

The mosaic of autoimmunity–Finally discussing in person. The 13th international congress on autoimmunity 2022 (AUTO13) Athens

N Mahroum, A Elsalti, A Alwani, I Seida, M Alrais… - Autoimmunity …, 2022 - Elsevier
While autoimmunity is a branch of medicine linked to every single organ system via direct
and indirect pathways, meeting in person to discuss autoimmunity during the 13 th …

SARS-CoV-2 and multiple sclerosis: potential for disease exacerbation

M MacDougall, J El-Hajj Sleiman… - Frontiers in …, 2022 - frontiersin.org
While the respiratory tract is the primary route of entry for SARS-CoV-2, evidence shows that
the virus also impacts the central nervous system. Intriguingly, case reports have …

[HTML][HTML] Interleukin-17A (IL-17A): A silent amplifier of COVID-19

F Maione, GM Casillo, F Raucci, C Salvatore… - Biomedicine & …, 2021 - Elsevier
One of the hallmarks of COVID-19 is the cytokine storm that provokes primarily pneumonia
followed by systemic inflammation. Emerging evidence has identified a potential link …