Advances in platelet subpopulation research

G Lesyk, P Jurasz - Frontiers in cardiovascular medicine, 2019 - frontiersin.org
Although lacking a nucleus, platelets are increasingly recognized not only for their
complexity, but also for their diversity. Some 50 years ago platelet subpopulations were …

Targeted platelet with hydrogen peroxide responsive behavior for non-alcoholic steatohepatitis detection

J Liu, X Liu, Y Shan, HJ Ting, X Yu, JW Wang, B Liu - Biomaterials, 2024 - Elsevier
The most common chronic liver illness, non-alcoholic fatty liver disease (NAFLD), refers to a
range of abnormalities of the liver with varying degrees of steatosis. When the clinical …

The Effect of Leukocyte Removal and Matrix Metalloproteinase Inhibition on Platelet Storage Lesions

A Rak-Pasikowska, K Hałucha, A Sapa-Wojciechowska… - Cells, 2024 - mdpi.com
The reasons for unfavorable changes in platelet concentrate (PC) quality during storage are
not fully understood yet. We aimed to evaluate whether leukocytes and matrix …

Design evolution and performance study of a reliable platelet-rich plasma microdevice

V Laxmi, SS Joshi, A Agrawal - Industrial & Engineering Chemistry …, 2020 - ACS Publications
Separation and enrichment of platelets from whole blood find numerous applications for
biomedical research, dermatology, and transfusion purposes. Therefore, there is a great …

Staphylococcal Enterotoxins Enhance Biofilm Formation by Staphylococcus aureus in Platelet Concentrates

SI Chi, S Ramirez-Arcos - Microorganisms, 2022 - mdpi.com
Biofilm formation and slow growth by Staphylococcus aureus in platelet concentrates (PCs)
cause missed detection of this bacterium during routine PC screening with automated …

[HTML][HTML] Developing a Multichannel Bioreactor with a Collagen Scaffold, ECM, and Cryoprecipitate to Significantly Produce Platelets from Umbilical Cord Blood Stem …

MHD Gonbad, AB Khoshfetrat… - … -Oncology and Stem …, 2023 - ncbi.nlm.nih.gov
Background: Platelets play a key role in the treatment of thrombocytopenia. Nowadays,
platelets (PLTs) are only obtained through blood donation. However, due to the limitations in …

Efficient Production of Platelets from Umbilical Cord Blood Stem Cells Using A Collagen-Tragacanth Scaffold in A Multi-Chamber Bioreactor

MH Derakhty Gonbad, AA Movassaghpour… - Iranian Journal of …, 2023 - ijpho.ssu.ac.ir
Background: To date, platelet (PLT) transfusion is the main medical option for the treatment
of thrombocytopenia. Nowadays, allogenic PLTs are commonly used for blood donation …

High Autophagy Patterns in Swelling Platelets During Apheresis Platelet Storage

L Yu, S Yu, Y He, G Deng, Q Li - Indian Journal of Hematology and Blood …, 2023 - Springer
Platelets undergo remarkable morphological changes during storage. Platelets change into
different sizes and densities and differ in their biochemistry and functions. However, the …

Assessment of apheresis platelets during 5 days of storage: A National Cancer Institute, Cairo University experience

EM Radwan, RM Allam, RMA El Fetouh… - … and Apheresis Science, 2022 - Elsevier
Background Platelet transfusion therapy is widely used to prevent hemorrhage in patients
with thrombocytopenia and platelet disorders. The platelet concentrate (PC) quality is …

Comparative analysis of platelet storage lesion in whole-blood-derived platelets stored in autologous plasma versus platelets stored in platelet additive solution using …

S Das, MLH Kumar - Global Journal of Transfusion Medicine, 2019 - journals.lww.com
Background: Platelets storage lesions remain a challenge in regular blood transfusion
services. Flow cytometric study based on the expression of platelets activation markers in …