Recurrent pregnancy loss

E Dimitriadis, E Menkhorst, S Saito… - Nature reviews disease …, 2020 - nature.com
Recurrent pregnancy loss is a distressing pregnancy disorder experienced by~ 2.5% of
women trying to conceive. Recurrent pregnancy loss is defined as the failure of two or more …

The role of oxidative stress and antioxidant balance in pregnancy

T Hussain, G Murtaza, E Metwally… - Mediators of …, 2021 - Wiley Online Library
It has been widely known that oxidative stress disrupts the balance between reactive oxygen
species (ROS) and the antioxidant system in the body. During pregnancy, the physiological …

Recurrent pregnancy loss etiology, risk factors, diagnosis, and management. Fresh look into a full box

A Turesheva, G Aimagambetova, T Ukybassova… - Journal of clinical …, 2023 - mdpi.com
Recurrent pregnancy loss is a complex health challenge with no universally accepted
definition. Inconsistency in definitions involves not only the number of spontaneous …

Pregnancy complications and later life women's health

C McNestry, SL Killeen, RK Crowley… - Acta Obstetricia et …, 2023 - Wiley Online Library
There has been increasing recognition of the association between various pregnancy
complications and development of chronic disease in later life. Pregnancy has come to be …

The role of uterine natural killer cells on recurrent miscarriage and recurrent implantation failure: from pathophysiology to treatment

K Sfakianoudis, A Rapani, S Grigoriadis, A Pantou… - Biomedicines, 2021 - mdpi.com
Uterine natural killer (uNK) cells constitute a unique uterine leucocyte subpopulation
facilitating implantation and maintaining pregnancy. Herein, we critically analyze current …

NLRP3 inflammasome: a new therapeutic target for high-risk reproductive disorders?

F Zhou, C Li, SY Zhang - Chinese medical journal, 2021 - journals.lww.com
The NOD-like receptor protein 3 (NLRP3) inflammasome is a key regulator of the host's
immune response, and many immune and metabolic disorders are linked to its activation …

Evaluation of T cell cytokines and their role in recurrent miscarriage

S Ali, S Majid, MN Ali, S Taing - International immunopharmacology, 2020 - Elsevier
Recurrent miscarriage (RM) is defined as two or more consecutive pregnancy losses that
affect approximately 5% of conceived women worldwide. RM is a multi-factorial reproductive …

Immunomodulatory activity-guided isolation and characterization of a novel polysaccharide from Atractylodis macrocephalae Koidz

W Xue, Y Gao, Q Li, Q Lu, Z Bian, L Tang… - International Journal of …, 2020 - Elsevier
Abstract The Rhizoma of Atractylodis macrocephala Koidz. is a traditional Chinese herbal
medicine that has been widely and empirically used for unexplained recurrent spontaneous …

A potential new mechanism for pregnancy loss: considering the role of LINE-1 retrotransposons in early spontaneous miscarriage

C Lou, JL Goodier, R Qiang - Reproductive Biology and Endocrinology, 2020 - Springer
LINE1 retrotransposons are mobile DNA elements that copy and paste themselves into new
sites in the genome. To ensure their evolutionary success, heritable new LINE-1 insertions …

[HTML][HTML] The exploration of Hashimoto's Thyroiditis related miscarriage for better treatment modalities

Y Min, X Wang, H Chen, G Yin - International journal of medical …, 2020 - ncbi.nlm.nih.gov
Hashimoto's thyroiditis (HT) is the most prevalent autoimmune thyroid disease (ATD)
worldwide and is strongly associated with miscarriage and even recurrent miscarriage (RM) …